SCHEMBL3248349

SCHEMBL3248349

CC(CO)CC(C)(CO)COCCO

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11217494 0.85 HSD17B10 (0.34)
SCHEMBL9634150 0.80 TSHR (0.45) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL4426678 0.79 TSHR (0.30) TSHR
SCHEMBL6282683 0.77 TSHR (0.38) TSHR
Di(Hydroxyethyl)Ether SCHEMBL28287703 0.77 TSHR (0.40) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL505525 0.75 TSHR (0.50) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL11278864 0.72 ALDH1A1 (0.34) ALDH1A1
SCHEMBL6271015 0.71
SCHEMBL23250821 0.71 MEN1 (0.58) ALDH1A1TSHRMAPK1MEN1KMT2A
Di(Hydroxyethyl)Ether SCHEMBL4933171 0.70 TSHR (0.59) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087562-A1 Polyurethane Foam Batt Insulation DILORETO SALVATORE ANTHONY 2010-04-08 US claimed
EP-2126234-A1 POLYURETHANE FOAM BATT INSULATION Diloreto, Salvatore Anthony (CA) 2009-12-02 EP claimed
US-20090053490-A1 Highly Filled Composite Materials CLAUSI ROBERT N 2009-02-26 US claimed
EP-1991608-A1 HIGHLY FILLED COMPOSITE MATERIALS Clausi, Robert N. (CA) 2008-11-19 EP claimed
WO-2008106801-A1 POLYURETHANE FOAM BATT INSULATION DILORETO SALVATORE ANTHONY (CA) 2008-09-12 WO claimed
WO-2007095730-A1 HIGHLY FILLED COMPOSITE MATERIALS CLAUSI ROBERT N (CA) 2007-08-30 WO claimed
WO-2019055607-A1 METHODS OF MANUFACTURE OF A BORON NITRIDE FOAM ROGERS CORPORATION (US) 2019-03-21 WO disclosed
WO-2018075302-A1 METHOD FOR DELAYING CURING IN POLYURETHANE AND COMPOSITIONS AND ARTICLES MADE THEREFROM ROGERS CORPORATION (US) 2018-04-26 WO disclosed
WO-2018048831-A1 COMPRESSIBLE THERMALLY CONDUCTIVE ARTICLES ROGERS CORPORATION (US) 2018-03-15 WO disclosed
WO-2016127016-A1 FOAM PRODUCTS AND METHODS OF PRODUCING THE SAME ROGERS CORPORATION (US) 2016-08-11 WO disclosed
WO-2015187439-A1 COMPRESSIBLE THERMALLY CONDUCTIVE ARTICLES ROGERS CORPORATION (US) 2015-12-10 WO disclosed
WO-2008097570-A2 CONDUCTIVE POLYMER FOAMS, METHOD OF MANUFACTURE, AND USES THEREOF WORLD PROPERTIES, INC. (US) 2008-08-14 WO disclosed
WO-2003091308-A1 FLAME RETARDANT POLYURETHANE COMPOSITION AND METHOD OF MANUFACTURE THEREOF WORLD PROPERTIES INC. (US) 2003-11-06 WO disclosed
US-3979420-A FLAME RETARDERS FOR POLYETHERURETHANE COPOLYMERS UNION CARBIDE CORPORATION (US) 1976-09-07 US disclosed
US-3966784-A CYANOALKYL MODIFIED SILOXANE FLUID UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed
US-3966650-A HIGH RESILIENCE, CYANOALKOXY-ALKYL MODIFIED SILOXANE FLUID UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed
US-3957842-A FOAM STABILIZERS UNION CARBIDE CORPORATION (US) 1976-05-18 US disclosed
US-3952038-A CYANOALKYL MODIFIED SILOXANE FLUID UNION CARBIDE CORPORATION (US) 1976-04-20 US disclosed
US-3947386-A Polyurethane foams stabilized with hydrolyzable polysiloxane copolymers UNION CARBIDE CORPORATION (US) 1976-03-30 US disclosed
US-3935123-A Polysiloxane-polyoxyalkylene compositions used in polyurethane foam UNION CARBIDE CORPORATION (US) 1976-01-27 US disclosed