Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27100322 | 0.89 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL505525 | 0.89 | TSHR (0.50) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10141555 | 0.85 | — | — | |
| SCHEMBL23250821 | 0.84 | MEN1 (0.58) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11026580 | 0.83 | CYP4F2 (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL284203 | 0.83 | — | — | |
| SCHEMBL2742280 | 0.82 | HSD17B10 (0.36) | TSHRALDH1A1 | |
| SCHEMBL284658 | 0.80 | — | — | |
| SCHEMBL283952 | 0.80 | — | — | |
| SCHEMBL16153826 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5156775-A | Flame retardant compositions | BLOUNT DAVID H (US) | 1992-10-20 | — | — | US | disclosed |
| US-4885381-A | Phosphate-phosphites acid halides | THE DOW CHEMICAL COMPANY (US) | 1989-12-05 | — | — | US | disclosed |
| US-4755547-A | Halogenated phosphate-phosphites and their acid halides and acids | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |