SCHEMBL3248700

SCHEMBL3248700

CCOCC1(C)c2cc(S(C)(=O)=O)ccc2N2CCOC21C=Cc1ccc(N(C)C)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MAPT P10636 4/20 0.32
▸ APP P05067 3/20 0.32
▸ SNCA P37840 2/20 0.32
▸ MAOB P27338 2/20 0.32
▸ GAA P10253 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ PKM P14618 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ NSD2 O96028 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3252515 1.00 MEN1 (0.33) MEN1KMT2AMAPTAPPSNCA
SCHEMBL3248701 1.00 MEN1 (0.33) MEN1KMT2AMAPTAPPSNCA
SCHEMBL3244927 0.85 MAPT (0.39) MEN1KMT2AMAPTAPPSNCA
SCHEMBL3254720 0.85 MEN1 (0.39) MEN1KMT2AMAPTAPPMAOB
SCHEMBL3244931 0.85 MAPT (0.39) MEN1KMT2AMAPTAPPSNCA
SCHEMBL3246291 0.85 MEN1 (0.39) MEN1KMT2AMAPTAPPMAOB
SCHEMBL3246695 0.85 MAPT (0.39) MEN1KMT2AMAPTAPPSNCA
SCHEMBL3257744 0.80 MEN1 (0.37) MEN1KMT2AMAPTAPPMAOB
SCHEMBL3246665 0.80 MEN1 (0.37) MEN1KMT2AMAPTAPPMAOB
SCHEMBL12311094 0.80 MEN1 (0.37) MEN1KMT2AMAPTAPPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747774-B1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres OREAL (FR) 2010-05-05 — — EP claimed
US-7585332-B2 Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device L'OREAL S.A. (FR) 2009-09-08 — — US claimed
US-7399319-B2 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2008-07-15 — — US claimed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US claimed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP claimed
EP-1747774-B1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres OREAL (FR) 2010-05-05 — — EP disclosed
EP-2083923-B1 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE OREAL (FR) 2010-05-05 — — EP disclosed
US-7585332-B2 Composition containing a styryl or imine type dye and a thiol compound, hair coloring process and device L'OREAL S.A. (FR) 2009-09-08 — — US disclosed
EP-2083790-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'Oreal (FR) 2009-08-05 — — EP disclosed
EP-2083923-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'Oreal (FR) 2009-08-05 — — EP disclosed
US-7527654-B2 Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process L'OREAL S.A. (FR) 2009-05-05 — — US disclosed
US-20090019645-A1 UNKNOWN L'OREAL S.A. (FR) 2009-01-22 — — US disclosed
US-20080189878-A1 Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process L'OREAL S.A. (FR) 2008-08-14 — — US disclosed
US-7399319-B2 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2008-07-15 — — US disclosed
WO-2008043967-A2 DYEING PROCESS USING A DYE OF STYRYL OR IMINE TYPE IN COMBINATION WITH A WEAK ACID AND DEVICE FOR IMPLEMENTING THE PROCESS L'OREAL (FR) 2008-04-17 — — WO disclosed
WO-2008043968-A2 COMPOSITION COMPRISING A DYE OF STYRYL OR IMINE TYPE AND A THIOL COMPOUND, DYEING PROCESS AND DEVICE L'OREAL (FR) 2008-04-17 — — WO disclosed
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers L'OREAL S.A. (FR) 2007-08-02 — — US disclosed
EP-1747774-A1 Use of a composition comprising a colouring agent of the styrylic or imino type for dyeing keratinuous fibres L'Oréal (FR) 2007-01-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090019645-A1 UNKNOWN KRT18, SQOR, MT-ND5 MEN1 3959/4885KMT2A 1588/4885MAPT 1040/4885
US-20080189878-A1 Dyeing process using a dye of styryl or imine type in combination with a weak acid, and device for implementing the process KRT18, INHA, IK MEN1 2999/4885KMT2A 809/4885MAPT 854/4885
US-20070174977-A1 Dyeing composition comprising a dye chosen from styryl and imine dyes and methods for dyeing keratin fibers KRT18, INHA, IK MEN1 3368/4885KMT2A 1891/4885MAPT 1182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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