Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 19/20 | 0.68 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238765 | 0.89 | ROCK2 (0.68) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3249964 | 0.89 | ROCK2 (0.71) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3244866 | 0.87 | ROCK2 (0.90) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3252994 | 0.84 | ROCK2 (0.49) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3249420 | 0.81 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3236255 | 0.80 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL3251679 | 0.79 | ROCK2 (0.84) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3246883 | 0.78 | ROCK2 (0.55) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3240681 | 0.76 | ROCK2 (1.00) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3244974 | 0.75 | ROCK2 (0.65) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |