Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 0.65 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247331 | 0.79 | ROCK2 (0.51) | ROCK2ROCK1FAAHMAPT | |
| SCHEMBL3249420 | 0.79 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL3248774 | 0.75 | ROCK2 (0.68) | ROCK2ROCK1 | |
| SCHEMBL3238765 | 0.75 | ROCK2 (0.68) | ROCK2ROCK1 | |
| SCHEMBL3249964 | 0.75 | ROCK2 (0.71) | ROCK2ROCK1 | |
| SCHEMBL1648107 | 0.74 | ROCK2 (0.70) | ROCK2ROCK1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL3244866 | 0.73 | ROCK2 (0.90) | ROCK2ROCK1 | |
| SCHEMBL3264992 | 0.71 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL3236255 | 0.70 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL15580002 | 0.69 | SMN1; SMN2 (0.63) | SMN1; SMN2HSD17B10MAPTHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |