SCHEMBL3249138

SCHEMBL3249138

O=C(O)c1cnc2cccnc2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
EGLN1 Q9GZT9 7/20 0.50
KDM4E B2RXH2 5/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
KDM4A O75164 2/20 0.50
KDM6B O15054 1/20 0.50
KDM6A O15550 1/20 0.50
TET3 O43151 1/20 0.50
KDM4B O94953 1/20 0.50
KDM5C P41229 1/20 0.50
KDM4D Q6B0I6 1/20 0.50
TET2 Q6N021 1/20 0.50
ALKBH5 Q6P6C2 1/20 0.50
TET1 Q8NFU7 1/20 0.50
FTO Q9C0B1 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50
KDM3A Q9Y4C1 1/20 0.50
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11567115 0.98 ALDH1A1 (0.57) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL12564546 0.88 ALDH1A1 (0.45) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL10877533 0.85 ALDH1A1 (0.45) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL10877535 0.85 PARP1 (0.51) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL11729968 0.85 ALDH1A1 (0.45) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL9872674 0.84 ALDH1A1 (0.45) ALDH1A1EGLN1LMNAALOX12CYP3A4
Hydrochloric Acid SCHEMBL11567111 0.83 ALDH1A1 (0.44) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL29532238 0.81 KDM4E (0.48) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL5259859 0.81 NAPRT (0.51) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A
SCHEMBL15738360 0.81 KDM4E (0.46) ALDH1A1EGLN1KDM4EL3MBTL1KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117684330-A Elastic felt for deep cooling 威伦维客节能科技(安徽)有限公司 2024-03-12 CN claimed
CN-109223779-A A kind of pharmaceutical composition and its preparation method and application promoting union 苏涛 2019-01-18 CN claimed
CN-117684330-A Elastic felt for deep cooling 威伦维客节能科技(安徽)有限公司 2024-03-12 CN disclosed
CN-117684330-A Elastic felt for deep cooling 威伦维客节能科技(安徽)有限公司 2024-03-12 CN disclosed
CN-109223779-A A kind of pharmaceutical composition and its preparation method and application promoting union 苏涛 2019-01-18 CN disclosed
EP-2181996-A1 Aminopiperidine derivatives GLAXO GROUP LIMITED (GB) 2010-05-05 EP disclosed
US-20100081650-A1 Antimicrobial Compounds AXTEN JEFFREY MICHAEL 2010-04-01 US disclosed
US-7622481-B2 Antibacterial compounds GLAXO GROUP LIMITED (GB) 2009-11-24 US disclosed
US-7534793-B2 Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity SMITHKLINE BEECHAM P.L.C. (GB) 2009-05-19 US disclosed
EP-1537123-B1 AMINO-SUBSTITUTED CYCLOHEXANE DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS GLAXO GROUP LTD (GB) 2009-04-29 EP disclosed
US-7498326-B2 Compounds GLAXO GROUP LIMITED (GB) 2009-03-03 US disclosed
US-4198504-A ANTIBIOTIC BRISTOL-MYERS COMPANY (US) 1980-04-15 US disclosed
EP-0006688-A1 Dimethyl sulfoxide adducts of sodium 6-(D(-)-alpha-(4-hydroxy-1,5-naphthyridine-3-carboxamido)phenylacetamido)penicillanate or the derivative thereof bearing a hydroxyl group at the p-position of the phenyl group, methods for their preparation and decomposition, and their use as intermediates for purifying the crude penicillins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-01-09 EP disclosed
US-4138554-A 7-[D-α-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-phenyl (and p-hydroxyphenyl)acetamido]-3-carbamoyloxymethyl-3-cephem-4-carboxylic acids BRISTOL-MYERS COMPANY (US) 1979-02-06 US disclosed
US-4026881-A 6-(D-2-[4-hydroxy-1,5-naphthyridine-3-carboxamido]-2-[4-hydroxyphenyl]acetamido)-2,2-dimethyl-3-(5-tetrazolyl)penam PFIZER INC. (US) 1977-05-31 US disclosed
US-4005075-A Penicillins and their preparation SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-25 US disclosed
US-4003887-A ANTIMICROBIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-18 US disclosed
US-3992371-A BACTERICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-16 US disclosed
US-3954733-A ANTIBIOTIC SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-05-04 US disclosed
US-3945995-A ANTIBIOTICS, PENICILLIN SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081650-A1 Antimicrobial Compounds ELANE, NISCH, PIGS ALDH1A1 2504/4885EGLN1 103/4885KDM4E 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.