Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5671785 | 0.88 | MAPT (0.41) | HTTPPARAKDM4EHPGDHSD17B10 | |
| SCHEMBL5669455 | 0.87 | KDM4E (0.44) | KDM4EKMT2AMEN1RECQLCA12 | |
| SCHEMBL2421654 | 0.86 | HTT (0.45) | HTTKDM4EKMT2AMEN1RECQL | |
| SCHEMBL5669374 | 0.84 | KDM4E (0.42) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL3249278 | 0.78 | APEX1 (0.46) | HTTPPARAKDM4EKMT2AMEN1 | |
| SCHEMBL5667072 | 0.78 | CXCR2 (0.39) | KDM4EKMT2AMEN1RECQLCA12 | |
| SCHEMBL5667800 | 0.78 | KDM4E (0.38) | HTTKDM4EKMT2AMEN1RECQL | |
| SCHEMBL5666941 | 0.74 | KDM4E (0.50) | KDM4EKMT2AMEN1RECQLCA12 | |
| SCHEMBL2424260 | 0.74 | MAPT (0.43) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL19331451 | 0.74 | KDM4E (0.56) | HTTKDM4EKMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315709-B1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2010-05-26 | — | — | EP | disclosed |
| EP-1315709-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002016339-A1 | AMINOALKYLBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-02-28 | — | — | WO | disclosed |