Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578080 | 0.78 | HRH3 (0.37) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL17591101 | 0.78 | CYP3A4 (0.39) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL3261204 | 0.77 | TLR8 (0.39) | MEN1MAPTKMT2ATDP1LIPG | |
| SCHEMBL11765109 | 0.77 | HRH3 (0.40) | MAPTALOX15TDP1HCAR2HCAR3 | |
| SCHEMBL12235362 | 0.73 | ALDH1A1 (0.43) | TP53MEN1MAPTALOX15TSHR | |
| SCHEMBL8235993 | 0.72 | HRH3 (0.42) | CYP3A4ALOX15ADORA3ADORA2A | |
| SCHEMBL31287983 | 0.72 | HCAR2 (0.41) | ALOX5CYP3A4TYRTP53MEN1 | |
| SCHEMBL4372160 | 0.72 | PARP1 (0.38) | MAPTALOX15HCAR2HCAR3ALDH1A1 | |
| SCHEMBL17224796 | 0.68 | KDM4E (0.49) | HCAR2HCAR3KDM4EALDH1A1HSD17B10 | |
| SCHEMBL3399692 | 0.67 | NOS1 (0.46) | ALOX5CYP3A4MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217131-B2 | Method for extracting a metal particulate from an aqueous solution using a sol-gel derived sorbent | ABS MATERIALS, INC. (US) | 2012-07-10 | — | — | US | claimed |
| WO-2011162836-A1 | METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT | ABS MATERIALS, INC (US) | 2011-12-29 | — | — | WO | claimed |
| US-20110132845-A1 | METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT | AQUANEX TECHNOLOGIES, LLC | 2011-06-09 | — | — | US | claimed |
| US-8217131-B2 | Method for extracting a metal particulate from an aqueous solution using a sol-gel derived sorbent | ABS MATERIALS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-8093251-B2 | Nitrogen-containing heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| WO-2011162836-A1 | METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT | ABS MATERIALS, INC (US) | 2011-12-29 | — | — | WO | disclosed |
| US-8026368-B2 | Hydrazide compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-09-27 | — | — | US | disclosed |
| US-20110132845-A1 | METHOD FOR EXTRACTING A METAL PARTICULATE FROM AN AQUEOUS SOLUTION USING A SOL-GEL DERIVED SORBENT | AQUANEX TECHNOLOGIES, LLC | 2011-06-09 | — | — | US | disclosed |
| US-20090253751-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| US-20090198060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-2025671-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| EP-1947101-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-4036812-A | ULTRAVIOLET STABILIZERS FOR POLYMERS | SANDOZ LTD. (CH) | 1977-07-19 | — | — | US | disclosed |
| US-3959265-A | NICKEL COMPLEXES; ULTRAVIOLET STABILIZERS | SANDOZ LTD. (CH) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198060-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | TEK, MPL, IL1RN | ALOX5 2074/4885CYP3A4 2936/4885TYR 723/4885 |
| US-20090253751-A1 | HYDRAZIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | TEK, THPO, PTAFR | ALOX5 2786/4885CYP3A4 2183/4885TYR 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.