Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.47 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.47 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238586 | 0.89 | ROCK2 (0.52) | ROCK2CDC42BPAMELKROCK1AKT1 | |
| SCHEMBL3239731 | 0.86 | ROCK2 (0.60) | ROCK2CDC42BPAROCK1 | |
| SCHEMBL3244191 | 0.86 | ROCK2 (0.52) | ROCK2CDC42BPAMELKROCK1 | |
| SCHEMBL3129499 | 0.85 | ROCK2 (0.45) | ROCK2CDC42BPAMELKROCK1AKT1 | |
| SCHEMBL3248596 | 0.85 | ROCK2 (0.53) | ROCK2CDC42BPAROCK1AKT1 | |
| SCHEMBL3248264 | 0.82 | ROCK2 (0.62) | ROCK2CDC42BPAROCK1 | |
| SCHEMBL3249765 | 0.80 | ROCK2 (0.51) | ROCK2MELKROCK1 | |
| SCHEMBL3252660 | 0.80 | ROCK2 (0.49) | ROCK2CDC42BPAROCK1AKT1 | |
| SCHEMBL3251847 | 0.78 | ROCK2 (0.55) | ROCK2CDC42BPAMELKROCK1 | |
| SCHEMBL3253611 | 0.78 | ROCK2 (0.61) | ROCK2CDC42BPAROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |