Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 14/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MELK | Q14680 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244191 | 0.85 | ROCK2 (0.52) | ROCK2ROCK1MELK | |
| SCHEMBL3248261 | 0.82 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL3249772 | 0.80 | ROCK2 (0.47) | ROCK2ROCK1MELK | |
| SCHEMBL3252655 | 0.79 | ROCK2 (0.56) | ROCK2ROCK1 | |
| SCHEMBL3247491 | 0.77 | ROCK2 (0.55) | ROCK2ROCK1 | |
| SCHEMBL3247373 | 0.73 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL3129499 | 0.72 | ROCK2 (0.45) | ROCK2ROCK1MELK | |
| SCHEMBL13391340 | 0.71 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL3249574 | 0.71 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL3251847 | 0.71 | ROCK2 (0.55) | ROCK2ROCK1MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |