⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841201 | 0.83 | — | — | |
| SCHEMBL8060996 | 0.83 | — | — | |
| SCHEMBL8625429 | 0.79 | — | — | |
| SCHEMBL7944682 | 0.79 | — | — | |
| SCHEMBL10862051 | 0.78 | — | — | |
| SCHEMBL9114078 | 0.76 | — | — | |
| SCHEMBL9114070 | 0.76 | — | — | |
| SCHEMBL9111719 | 0.75 | — | — | |
| SCHEMBL9111041 | 0.75 | FAAH (0.31) | — | |
| SCHEMBL9111714 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889723-B2 | Aminoalkyloxazole and aminoalkylthiazolecarboxylic acid amides as regeneration-promoting substances for sensory organs and post-mitotic tissues | EMC MICROCOLLECTIONS GMBH (DE) | 2014-11-18 | — | — | US | claimed |
| US-20140288135-A1 | AMINOALKYLOXAZOLE AND AMINOALKYLTHIAZOLECARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUES | EMC MICROCOLLECTIONS GMBH (DE) | 2014-09-25 | — | — | US | claimed |
| US-20130012514-A1 | AMINOALKYLOXAZOLE AND AMINOALKYLTHIAZOLECARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUE | EMC MICROCOLLECTIONS GMBH (DE) | 2013-01-10 | — | — | US | claimed |
| EP-2534139-A1 | NOVEL AMINOALKYL-OXAZOLE AND AMINOALKYL-THIAZOLE CARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUE | EMC Microcollections GmbH (DE) | 2012-12-19 | — | — | EP | claimed |
| WO-2011095338-A1 | NOVEL AMINOALKYL-OXAZOLE AND AMINOALKYL-THIAZOLE CARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUE | EMC MICROCOLLECTIONS GMBH (DE) | 2011-08-11 | — | — | WO | claimed |
| US-8889723-B2 | Aminoalkyloxazole and aminoalkylthiazolecarboxylic acid amides as regeneration-promoting substances for sensory organs and post-mitotic tissues | EMC MICROCOLLECTIONS GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889723-B2 | Aminoalkyloxazole and aminoalkylthiazolecarboxylic acid amides as regeneration-promoting substances for sensory organs and post-mitotic tissues | EMC MICROCOLLECTIONS GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8889723-B2 | Aminoalkyloxazole and aminoalkylthiazolecarboxylic acid amides as regeneration-promoting substances for sensory organs and post-mitotic tissues | EMC MICROCOLLECTIONS GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| US-20140288135-A1 | AMINOALKYLOXAZOLE AND AMINOALKYLTHIAZOLECARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUES | EMC MICROCOLLECTIONS GMBH (DE) | 2014-09-25 | — | — | US | disclosed |
| US-20140288135-A1 | AMINOALKYLOXAZOLE AND AMINOALKYLTHIAZOLECARBOXYLIC ACID AMIDES AS REGENERATION-PROMOTING SUBSTANCES FOR SENSORY ORGANS AND POST-MITOTIC TISSUES | EMC MICROCOLLECTIONS GMBH (DE) | 2014-09-25 | — | — | US | disclosed |
| US-8518928-B2 | Therapeutic compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-08-27 | — | — | US | disclosed |
| CN-102947281-A | Novel aminoalkyl-oxazole and aminoalkyl-thiazole carboxamides as regeneration-promoting substances for sensory organs and postmitotic tissues | EMC MICROCOLLECTIONS GMBH | 2013-02-27 | — | — | CN | disclosed |
| US-20040147565-A1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | G.D. SEARLE & CO. | 2004-07-29 | — | — | US | disclosed |
| US-6677364-B2 | ANTI-INFLAMMATORY, ANTIPYRETIC, ANALGESIC COMPOSITIONS | G.D. SEARLE & CO. | 2004-01-13 | — | — | US | disclosed |
| EP-0828736-B1 | SUBSTITUTED SULFONYLPHENYLHETEROCYCLES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | SEARLE & CO (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0995747-B1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | SEARLE & CO (US) | 2002-08-07 | — | — | EP | disclosed |
| US-20020086886-A1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | G.D. SEARLE & CO. | 2002-07-04 | — | — | US | disclosed |
| EP-0995747-A1 | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors | G.D. SEARLE & CO. (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0828736-A1 | SUBSTITUTED SULFONYLPHENYLHETEROCYCLES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038442-A1 | SUBSTITUTED SULFONYLPHENYLHETEROCYCLES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-12-05 | — | — | WO | disclosed |