⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13841201 | 0.79 | — | — | |
| SCHEMBL324978 | 0.79 | — | — | |
| SCHEMBL7944682 | 0.79 | — | — | |
| SCHEMBL10862051 | 0.78 | — | — | |
| SCHEMBL9114078 | 0.76 | — | — | |
| SCHEMBL9114070 | 0.76 | — | — | |
| SCHEMBL9111041 | 0.75 | FAAH (0.31) | — | |
| SCHEMBL9111714 | 0.75 | — | — | |
| SCHEMBL9111719 | 0.75 | — | — | |
| SCHEMBL9111046 | 0.75 | FAAH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709379-B1 | Process for the preparation of alkyloxazole derivatives fluorinated on a side chain | BAYER AG (DE) | 1998-01-14 | — | — | EP | claimed |
| US-5621111-A | Process for the preparation of side chain-fluorinated alkyloxazoles, and new side chain-fluorinated alkyloxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | claimed |
| JP-8225549-A | — | — | None | — | — | JP | disclosed |
| US-5621111-A | Process for the preparation of side chain-fluorinated alkyloxazoles, and new side chain-fluorinated alkyloxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5621111-A | Process for the preparation of side chain-fluorinated alkyloxazoles, and new side chain-fluorinated alkyloxazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| JP-H08225549-A | PRODUCTION OF SIDE-CHAIN FLUORINATED ALKYLOXAZOLE AND NEW SIDE-CHAIN ILUORINATED ALKYLOXAZOLE | BAYER AG | 1996-09-03 | — | — | JP | disclosed |
| EP-0709379-A1 | Process for the preparation of alkyloxazole derivatives fluorinated on a side chain and novel alkyloxazole derivatives fluorinated on a side chain | BAYER AG (DE) | 1996-05-01 | — | — | EP | disclosed |