Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6391108 | 0.81 | KDM4E (0.45) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL3241682 | 0.79 | KMT2A (0.46) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL1206338 | 0.74 | KDM4E (0.46) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL27840846 | 0.72 | ACHE (0.47) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL1257999 | 0.72 | ACHE (0.41) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL1179178 | 0.72 | HTT (0.44) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL8723662 | 0.72 | KMT2A (0.45) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL15486904 | 0.72 | ACHE (0.44) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 | |
| SCHEMBL1063629 | 0.70 | HDAC1 (0.67) | — | |
| SCHEMBL8723658 | 0.69 | KDM4E (0.44) | SMN1; SMN2KDM4EHTTKCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033824-A1 | SULFONAMIDE DERIVATIVES AS INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2010-03-25 | — | — | WO | disclosed |