Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206338 | 0.80 | KDM4E (0.46) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL3241682 | 0.80 | KMT2A (0.46) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8330483 | 0.76 | RAB9A (0.60) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8723662 | 0.75 | KMT2A (0.45) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6391108 | 0.74 | KDM4E (0.45) | KDM4ESMN1; SMN2HTTKMT2AALOX15 | |
| SCHEMBL27840846 | 0.73 | ACHE (0.47) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL1179178 | 0.73 | HTT (0.44) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL1201562 | 0.72 | UNG (0.45) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL15486904 | 0.70 | ACHE (0.44) | KDM4ESMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL1200850 | 0.69 | ACHE (0.46) | KDM4ESMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731472-A | HETEROCYCLIC NITROGEN COMPOUNDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-03-24 | — | — | US | disclosed |