Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926014 | 0.92 | CYP2D6 (0.58) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL3247871 | 0.90 | ATM (0.58) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL11354054 | 0.87 | CYP2D6 (0.62) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| Hydrochloric Acid SCHEMBL16113966 | 0.85 | CYP2D6 (0.60) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL845626 | 0.78 | CYP2D6 (0.56) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL15282667 | 0.78 | CYP2D6 (0.56) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| Water SCHEMBL5605435 | 0.76 | CYP2D6 (0.54) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL15670258 | 0.76 | CYP2D6 (0.64) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL3090690 | 0.76 | CYP2D6 (0.54) | CYP2D6ALDH1A1MAPTMEN1HPGD | |
| SCHEMBL29910990 | 0.76 | CYP2D6 (0.54) | CYP2D6ALDH1A1MAPTMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249937-A | Novel naphthalimide sulfonate derivative, photoacid generator comprising the same, and photoresist composition comprising the same | 株式会社三养社 | 2023-06-09 | — | — | CN | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | CYP2D6 2600/4885ALDH1A1 874/4885MAPT 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.