Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926014 | 0.98 | CYP2D6 (0.58) | ATMCYP2D6BCHEMEN1ALDH1A1 | |
| SCHEMBL3249871 | 0.90 | CYP2D6 (0.61) | ATMCYP2D6MEN1ALDH1A1MAPT | |
| SCHEMBL5830749 | 0.84 | BCHE (0.61) | ATMBCHENPSR1EPHX1SIGMAR1 | |
| SCHEMBL11354054 | 0.81 | CYP2D6 (0.62) | ATMCYP2D6MEN1ALDH1A1MAPT | |
| SCHEMBL9529506 | 0.81 | BCHE (0.66) | ATMBCHENPSR1EPHX1SIGMAR1 | |
| SCHEMBL30449895 | 0.81 | ATM (0.43) | ATMCYP2D6BCHEALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL16113966 | 0.80 | CYP2D6 (0.60) | ATMCYP2D6MEN1ALDH1A1MAPT | |
| SCHEMBL9749544 | 0.79 | GAA (0.53) | CYP2D6ALDH1A1MAPTKMT2ACYP1A2 | |
| SCHEMBL7738571 | 0.77 | KDM4E (0.49) | ATMMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7741436 | 0.77 | KDM4E (0.49) | ATMMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111302880-B | Application of iron catalyst in reduction coupling reaction and preparation method of aromatic ring and heterocyclic derivative | 川北医学院 | 2022-09-13 | — | — | CN | claimed |
| CN-1893916-B | Cosmetic and dermatologic oxygen carrier system | COTY BV | 2010-05-26 | — | — | CN | claimed |
| CN-111302880-B | Application of iron catalyst in reduction coupling reaction and preparation method of aromatic ring and heterocyclic derivative | 川北医学院 | 2022-09-13 | — | — | CN | disclosed |
| CN-111302880-A | Application of iron catalyst in reduction coupling reaction and preparation method of aromatic ring and heterocyclic derivative | 川北医学院 | 2020-06-19 | — | — | CN | disclosed |
| CN-1893916-B | Cosmetic and dermatologic oxygen carrier system | COTY BV | 2010-05-26 | — | — | CN | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| CN-1893916-A | Cosmetic and dermatologic oxygen carrier system | COTY BV (NL) | 2007-01-10 | — | — | CN | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| CN-1058002-C | Method for treatment of mixture of hydroperoxide | SUMITOMO CHEMICAL CO (JP) | 2000-11-01 | — | — | CN | disclosed |
| US-5639922-A | CONTACTING AROMATIC PRIMARY AND TERTIARY HYDROPEROXIDES MIXTURE OBTAINED BY OXIDATION OF ALKYLAROMATIC COMPOUNDS WITH AN ALKALI OR ALKALINE ORGANIC AROMATIC CARBOXYLIC ACID SALT, DECOMPOSING WITH ACID CATALYST FORMING ALKYL PHENOLS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| CN-1128754-A | Method for treatment of mixture of hydroperoxide | SUMITOMO CHEMICAL CO (JP) | 1996-08-14 | — | — | CN | disclosed |
| WO-1994024132-A1 | TETRAHYDRO-PYRIDO-INDOLE | ELI LILLY AND COMPANY (US) | 1994-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | ATM 225/4885CYP2D6 2600/4885BCHE 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.