Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL3895453 | 1.00 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2049859 | 0.92 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27777399 | 0.91 | TSHR (0.55) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27839875 | 0.90 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL3249925 | 0.90 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL3741434 | 0.89 | TSHR (0.52) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10970615 | 0.87 | TSHR (0.57) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL11775670 | 0.86 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL27534277 | 0.86 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL448283 | 0.85 | TSHR (0.80) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244790-B2 | Thermoplastic elastomer blend, method of manufacture and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-07-17 | — | — | US | claimed |
| WO-2023132630-A2 | BIODEGRADABLE THERMOPLASTIC POLYETHER ESTER ELASTOMER | 이성율 | 2023-07-13 | — | — | WO | disclosed |
| EP-1877489-B1 | THERMOPLASTIC ELASTOMER BLEND, METHOD OF MANUFACTURE AND USE THEREOF | DU PONT (US) | 2009-09-16 | — | — | EP | disclosed |
| US-7531593-B2 | Thermoplastic elastomer blend composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-12 | — | — | US | disclosed |
| WO-2008054776-A1 | THERMOPLASTIC ELASTOMER BLEND COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20080103243-A1 | Thermoplastic elastomer blend composition | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-05-01 | — | — | US | disclosed |
| EP-1877489-A1 | THERMOPLASTIC ELASTOMER BLEND, METHOD OF MANUFACTURE AND USE THEREOF | E.I.Du pont de nemours and company (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006119059-A1 | THERMOPLASTIC ELASTOMER BLEND, METHOD OF MANUFACTURE AND USE THEREOF | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-09 | — | — | WO | disclosed |