SCHEMBL3249956

SCHEMBL3249956

CC(=O)Nc1ccc(S(=O)(=O)NCCSSCCNS(=O)(=O)c2ccc(NC(C)=O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.79
ALDH1A1 P00352 4/20 0.64
KMT2A Q03164 4/20 0.64
MEN1 O00255 3/20 0.64
NPSR1 Q6W5P4 1/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
HTT P42858 3/20 0.64
MAPT P10636 3/20 0.64
USP2 O75604 1/20 0.64
TSHR P16473 1/20 0.64
LMNA P02545 4/20 0.62
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C19 P33261 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
MMP1 P03956 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17670526 0.90 POLB (0.77) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL17633853 0.86 POLB (0.71) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL9614881 0.84 POLB (0.84) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL16180691 0.83 POLB (0.82) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL2008204 0.82 POLB (0.79) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL28079515 0.82 POLB (0.79) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL4594909 0.82 POLB (0.79) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL4068451 0.81 POLB (0.78) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL12912609 0.81 POLB (0.77) POLBALDH1A1KMT2AMEN1NPSR1
SCHEMBL4066416 0.81 POLB (0.77) POLBALDH1A1KMT2AMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1225205-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-10-06 EP disclosed
EP-1942156-B1 Carbon black reacted with diazonium salts and products CABOT CORP (US) 2010-04-14 EP disclosed
EP-1942156-A1 Carbon black reacted with diazonium salts and products Cabot Corporation (US) 2008-07-09 EP disclosed
US-7294185-B2 In absence of exterior applies electrical current; wear resistance CABOT CORPORATION (US) 2007-11-13 US disclosed
EP-0799281-B2 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2006-03-29 EP disclosed
US-20050034629-A1 In absence of exterior applies electrical current; wear resistance BELMONT JAMES A (US) 2005-02-17 US disclosed
US-6740151-B2 IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT TO REDUCE THE DIAZONIUM SALT AND ATTACH AN ORGANIC GROUP; IMPROVED ABRASION RESISTANCE. CABOT CORPORATION 2004-05-25 US disclosed
US-20030095914-A1 In the absence of an externally applied electric current sufficient to reduce the diazonium salt and attach an organic group; improved abrasion resistance. BELMONT JAMES A (US) 2003-05-22 US disclosed
US-6494946-B1 PROCESSES FOR PREPARING A CARBON BLACK PRODUCT HAVING AN ORGANIC GROUP ATTACHED TO THE CARBON BLACK. IN ONE PROCESS AT LEAST ONE DIAZONIUM SALT REACTS WITH A CARBON BLACK IN THE ABSENCE OF AN EXTERNALLY APPLIED ELECTRIC CURRENT SUFFICIENT CABOT CORPORATION 2002-12-17 US disclosed
EP-0799281-B1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORP (US) 2002-07-24 EP disclosed
EP-1225205-A2 Carbon black reacted with diazonium salts and products CABOT CORPORATION (US) 2002-07-24 EP disclosed
US-6042643-A AS PIGMENT TO COLOR PLASTICS, PAPER, TEXTILE, RUBBER, AQUEOUS INKS CABOT CORPORATION (US) 2000-03-28 US disclosed
US-5900029-A COLORING FIBER OR TEXTILE CABOT CORPORATION (US) 1999-05-04 US disclosed
US-5851280-A Reaction of carbon black with diazonium salts, resultant carbon black products and their uses CABOT CORPORATION (US) 1998-12-22 US disclosed
EP-0799281-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1997-10-08 EP disclosed
WO-1996018688-A1 CARBON BLACK REACTED WITH DIAZONIUM SALTS AND PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed