Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13539033 | 0.85 | SMN1; SMN2 (0.63) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL18256154 | 0.83 | MAPT (0.72) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL5256099 | 0.81 | SMN1; SMN2 (0.70) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL4028624 | 0.80 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL6642379 | 0.80 | HTT (0.64) | MAPTALDH1A1KMT2AMEN1POLB | |
| Bromide SCHEMBL6428429 | 0.79 | MAPT (0.60) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL3005360 | 0.78 | UBE2T (0.63) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL3255804 | 0.77 | BCHE (0.50) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL3129362 | 0.76 | UBE2T (0.50) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL3125957 | 0.76 | SMN1; SMN2 (0.62) | ALDH1A1KMT2AMEN1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |