Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159541 | 0.89 | HPGD (0.55) | BCHEHPGDCYP1A2CYP2C19HTT | |
| SCHEMBL1981436 | 0.81 | BCHE (0.58) | BCHECYP1A2CYP2C19HTTHDAC3 | |
| SCHEMBL3250296 | 0.77 | MAPT (0.53) | HPGDCYP1A2CYP2C19HTTMAPT | |
| SCHEMBL25955151 | 0.75 | HDAC3 (0.49) | HPGDCYP1A2CYP2C19HTTHDAC3 | |
| SCHEMBL28366491 | 0.75 | DYRK1A (0.48) | HPGDRAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL30493007 | 0.75 | DYRK1A (0.48) | HPGDRAB9AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL15195148 | 0.75 | HPGD (0.58) | HPGDCYP1A2CYP2C19HTTMAPT | |
| SCHEMBL13539033 | 0.75 | SMN1; SMN2 (0.63) | HPGDCYP1A2CYP2C19HTTMAPT | |
| SCHEMBL5068294 | 0.75 | ALDH1A1 (0.53) | BCHEHPGDHDAC3HDAC4HDAC1 | |
| SCHEMBL22605044 | 0.74 | ATM (0.58) | BCHEKMT2AKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |