Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ILK | Q13418 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3005360 | 0.84 | UBE2T (0.63) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL13539033 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL14835424 | 0.79 | SMN1; SMN2 (0.67) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL8424171 | 0.76 | ALOX15 (0.63) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL3250296 | 0.76 | MAPT (0.53) | SMN1; SMN2ALOX15HTTHPGDPOLB | |
| SCHEMBL3125957 | 0.76 | SMN1; SMN2 (0.62) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL3919004 | 0.75 | UBE2T (0.61) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL11074021 | 0.75 | NPC1 (0.63) | SMN1; SMN2HPGDPOLBRAB9ANPC1 | |
| SCHEMBL30007395 | 0.75 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2ALOX15HTT | |
| SCHEMBL244157 | 0.75 | UBE2T (0.66) | UBE2TASIC3SMN1; SMN2ALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010001220-A1 | NEW 1,2,4-TRIAZINE DERIVATIVES AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS SA (FR) | 2010-01-07 | — | — | WO | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141164-A1 | New 1,2,4-triazine derivatives and biological applications thereof | Mutabilis (FR) | 2010-01-06 | — | — | EP | disclosed |