Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 14/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516946 | 0.86 | NFE2L2 (0.67) | NFE2L2RELA | |
| SCHEMBL3306938 | 0.84 | NFE2L2 (0.52) | NFE2L2 | |
| SCHEMBL2118262 | 0.84 | NFE2L2 (0.68) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2706933 | 0.82 | NFE2L2 (0.69) | NFE2L2RELA | |
| SCHEMBL8011556 | 0.82 | NFE2L2 (0.48) | NFE2L2RELAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8416900 | 0.81 | ALDH1A1 (0.45) | NFE2L2 | |
| SCHEMBL2091694 | 0.81 | NFE2L2 (0.55) | NFE2L2 | |
| SCHEMBL3292445 | 0.78 | NFE2L2 (1.00) | NFE2L2RELA | |
| SCHEMBL3292441 | 0.78 | NFE2L2 (1.00) | NFE2L2RELA | |
| SCHEMBL14401252 | 0.78 | NFE2L2 (1.00) | NFE2L2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768941-A | Alpha-diimine metal complex and preparation method and application thereof | 中国石化扬子石油化工有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-112322195-B | Ultraviolet light curing composition glue and use method and application thereof | 西安思摩威新材料有限公司 | 2023-05-16 | — | — | CN | claimed |
| US-8492384-B2 | Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-07-23 | — | — | US | claimed |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-12-31 | — | — | US | claimed |
| EP-1569645-A2 | METHOD OF USING AMINOCYANOPYRIDINE COMPOUNDS AS MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 INHIBITORS | Pharmacia Corporation (US) | 2005-09-07 | — | — | EP | claimed |
| EP-1569932-A1 | AMINOCYANOPYRIDINE INHIBITORS OF MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 | Pharmacia Corporation (US) | 2005-09-07 | — | — | EP | claimed |
| US-20040142978-A1 | Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION (US) | 2004-07-22 | — | — | US | claimed |
| WO-2004055015-A1 | AMINOCYANOPYRIDINE INHIBITORS OF MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 | PHARMACIA CORPORATION (US) | 2004-07-01 | — | — | WO | claimed |
| WO-2004054505-A2 | METHOD OF USING AMINOCYANOPYRIDINE COMPOUNDS AS MITOGEN ACTIVATED PROTEIN KINASE-ACTIVATED PROTEIN KINASE-2 INHIBITORS | PHARMACIA CORPORATION (US) | 2004-07-01 | — | — | WO | claimed |
| US-20040127519-A1 | Method of using aminocyanopyridine compounds as mitogen activated protein kinase-activated protein kinase-2 inhibitors | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | claimed |
| US-4404384-A | HYPOTENSIVE, ANTISPASMODIC, CHOLERETIC AGENTS; ANTICONUULSANTS; ANTIPYRETICS; ANTHELMINTICS; FUNGICIDWS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | claimed |
| CN-117003797-A | Alpha-diimine metal complex with tetracene skeleton and preparation method and application thereof | 中国石化扬子石油化工有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116768941-A | Alpha-diimine metal complex and preparation method and application thereof | 中国石化扬子石油化工有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-104250270-B | Asymmetric benzhydryl alpha-diimine nickel complex and preparation and application thereof | 中国石油天然气股份有限公司 | 2017-02-15 | — | — | CN | disclosed |
| WO-2016004093-A2 | THERAPEUTIC COMPOSITIONS INCLUDING GALECTIN-3 INHIBITORS AND USES THEREOF | STEALTH BIOTHERAPEUTICS CORP (MC) | 2016-01-07 | — | — | WO | disclosed |
| EP-0695296-A1 | 3-(HETERO)ARYLOXY(THIO) CARBOXYLIC ACID DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |
| WO-1995026716-A1 | PYRIMIDINE OR TRIAZINE CARBOXYLIC ACID DERIVATIVES TO BE USED AS MEDICAMENTS | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |
| WO-1994025443-A1 | 3-(HETERO)ARYLOXY(THIO) CARBOXYLIC ACID DERIVATIVES, METHOD OF PREPARING THEM AND INTERMEDIATES USED IN THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |
| US-5210205-A | Plant fungicide, thiazolocarboxamides, N-cyanoalkyl- | CIBA-GEIGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0090733-A1 | Disubstituted polymethylene imines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1983-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127519-A1 | Method of using aminocyanopyridine compounds as mitogen activated protein kinase-activated protein kinase-2 inhibitors | MAPKAPK2, MAP2K2, MAP3K2 | NFE2L2 1702/4885RELA 3000/4885GRIN2D 1233/4885 |
| US-20040142978-A1 | Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase-2 | MAP4K2, MAP3K20, MAPKAPK2 | NFE2L2 2821/4885RELA 2741/4885GRIN2D 766/4885 |
| US-20090325979-A1 | NOVEL IMIDAZOLYLALKYLCARBONYL DERIVATIVES AS CALCIUM CHANNEL MODULATORS AND PREPARATION METHOD THEREOF | CACNA1B, CACNA1C, ORAI1 | NFE2L2 3063/4885RELA 4004/4885GRIN2D 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.