Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 18/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3244470 | 0.85 | ROCK2 (0.42) | ROCK2ROCK1BCL9CTNNB1 | |
| SCHEMBL3249902 | 0.85 | ROCK2 (0.47) | ROCK2ROCK1 | |
| SCHEMBL3247220 | 0.82 | ROCK2 (0.47) | ROCK2ROCK1 | |
| SCHEMBL3238931 | 0.79 | ROCK2 (0.44) | ROCK2ROCK1 | |
| SCHEMBL3251649 | 0.78 | ROCK2 (0.44) | ROCK2ROCK1 | |
| SCHEMBL3245593 | 0.76 | ROCK2 (0.53) | ROCK2ROCK1 | |
| SCHEMBL3246278 | 0.76 | ROCK2 (0.44) | ROCK2ROCK1 | |
| SCHEMBL3248607 | 0.76 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL3252034 | 0.74 | ROCK2 (0.48) | ROCK2ROCK1 | |
| SCHEMBL3238595 | 0.74 | ROCK2 (0.48) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |