Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 14/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246520 | 0.91 | ROCK2 (0.59) | ROCK2ROCK1 | |
| SCHEMBL3248607 | 0.84 | ROCK2 (0.49) | ROCK2ROCK1KDR | |
| SCHEMBL3238595 | 0.83 | ROCK2 (0.48) | ROCK2ROCK1KDR | |
| SCHEMBL3244470 | 0.83 | ROCK2 (0.42) | ROCK2ROCK1KDR | |
| SCHEMBL3250849 | 0.82 | ROCK2 (0.43) | ROCK2ROCK1 | |
| SCHEMBL3251649 | 0.81 | ROCK2 (0.44) | ROCK2ROCK1KDR | |
| SCHEMBL3252034 | 0.80 | ROCK2 (0.48) | ROCK2ROCK1KDR | |
| SCHEMBL3246278 | 0.79 | ROCK2 (0.44) | ROCK2ROCK1KDR | |
| SCHEMBL3247209 | 0.78 | ROCK2 (0.52) | ROCK2ROCK1L3MBTL1KDRKIT | |
| SCHEMBL3254666 | 0.76 | ROCK2 (0.51) | ROCK2ROCK1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |