Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bentiromide SCHEMBL1001794 | 1.00 | CTSL (0.62) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| Bentiromide SCHEMBL151634 | 1.00 | CTSL (0.62) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| Bentiromide SCHEMBL9008617 | 0.94 | CTSL (0.56) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2903018 | 0.92 | CTSL (0.61) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2903012 | 0.92 | CTSL (0.61) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6407354 | 0.85 | NPC1 (0.57) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1351202 | 0.85 | CTSL (0.56) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29664572 | 0.85 | PKM (0.58) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29106092 | 0.85 | PKM (0.58) | CTSLHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6442235 | 0.85 | CTSL (0.56) | CTSLHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10809259-B2 | Protocol for preconcentration and quantification of microcystins using LC-MS | THE UNIVERSITY OF TOLEDO (US) | 2020-10-20 | — | — | US | disclosed |
| US-10722562-B2 | Combinatorial analysis and repair | IMMUDEX APS (DK) | 2020-07-28 | — | — | US | disclosed |
| US-10436794-B1 | Protocol for preconcentration and quantification of microcystins using LC-MS | THE UNIVERSITY OF TOLEDO (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180321237-A1 | Protocol for Preconcentration and Quantification of Microcystins Using LC-MS | THE UNIVERSITY OF TOLEDO (US) | 2018-11-08 | — | — | US | disclosed |
| WO-2010009735-A2 | COMBINATORIAL ANALYSIS AND REPAIR | DAKO DENMARK A/S (DK) | 2010-01-28 | — | — | WO | disclosed |
| US-5506147-A | BENTIROMIDE TEST FOR PANCREATIC FUNCTION: ADMINISTERING WITH A STABLE, NON-RADIOACTIVE ISOTOPE OF PARA-AMINOBENZOIC ACID; MEASURING NATURAL PABA AND PABA ISOTOPE BY GAS CHROMATOGRAPHY/MASS SPECTROSCOPY | DEUTSCH, JOHN D. | 1996-04-09 | — | — | US | disclosed |