Phthalimide

Phthalimide

SCHEMBL3251016

O=C1NC(=O)c2ccccc21.OCCOCCOCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.58
CASP3 P42574 1/20 0.50
CASP2 P42575 1/20 0.50
CASP7 P55210 1/20 0.50
CASP6 P55212 1/20 0.50
CASP8 Q14790 1/20 0.50
CCNB2 O95067 4/20 0.43
CDK1 P06493 4/20 0.43
CCNB1 P14635 4/20 0.43
CCNB3 Q8WWL7 4/20 0.43
GAA P10253 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAOA P21397 5/20 0.41
MAOB P27338 5/20 0.41
PARP1 P09874 1/20 0.39
PDGFRA P16234 1/20 0.39
FER P16591 1/20 0.39
LTK P29376 1/20 0.39
CDK8 P49336 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL2385574 1.00 GSK3B (0.58) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL4446059 0.98 GSK3B (0.60) GSK3BCASP3CASP2CASP7CASP6
Tetraethylene Glycol SCHEMBL8058824 0.92 GSK3B (0.48) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL8058821 0.86 GSK3B (0.43) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL2452324 0.83 GSK3B (0.75) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL10495310 0.78 GSK3B (0.65) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL10496306 0.78 GSK3B (0.65) GSK3BCASP3CASP2CASP7CASP6
Phthalimide SCHEMBL5215747 0.77 GSK3B (0.71) GSK3BCASP3CASP2CASP7CASP6
Phthalic Anhydride SCHEMBL185274 0.76 ALOX15 (0.58) GAAMEN1KMT2AMAPK1TSHR
Phthalimide SCHEMBL29366030 0.76 GSK3B (1.00) GSK3BCASP3CASP2CASP7CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1707963-B1 Magnetic particles having porous surfaces, method of producing the same, carrier for biochemical use, and biotin-bonding particles JSR CORP (JP) 2010-12-08 EP disclosed
EP-1837656-B1 Magnetic particles and method for producing the same JSR CORP (JP) 2010-05-19 EP disclosed
US-7713627-B2 Magnetic particles comprising an organic polymer layer and method for producing the same JSR CORPORATION (JP) 2010-05-11 US disclosed
US-20070224424-A1 MAGNETIC PARTICLES AND METHOD FOR PRODUCING THE SAME JSR CORPORATION (JP) 2007-09-27 US disclosed
EP-1837656-A1 Magnetic particles and method for producing the same JSR Corporation (JP) 2007-09-26 EP disclosed
US-20060223126-A1 Magnetic particles having porous surfaces, method of producing the same, carrier for biochemical use, and biotin-bonding particles JSR CORPORATION (JP) 2006-10-05 US disclosed
EP-1707963-A2 Magnetic particles having porous surfaces, method of producing the same, carrier for biochemical use, and biotin-bonding particles JSR Corporation (JP) 2006-10-04 EP disclosed