Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.42 |
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FER | P16591 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL3251016 | 0.92 | GSK3B (0.58) | GSK3BCASP3CASP2CASP7CASP6 | |
| Tetraethylene Glycol SCHEMBL2385574 | 0.92 | GSK3B (0.58) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL8058821 | 0.91 | GSK3B (0.43) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL4446059 | 0.90 | GSK3B (0.60) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL2452324 | 0.76 | GSK3B (0.75) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL10496306 | 0.75 | GSK3B (0.65) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL11199833 | 0.72 | GSK3B (0.75) | GSK3BCASP3CASP2CASP7CASP6 | |
| Phthalimide SCHEMBL28158464 | 0.72 | GSK3B (0.83) | GSK3BCASP3CASP2CASP7CASP6 | |
| Hexaethylene Glycol SCHEMBL1065217 | 0.72 | MEN1 (0.69) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| Tetraethylene Glycol SCHEMBL8446693 | 0.72 | MEN1 (0.69) | MEN1KMT2AMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015629-A1 | BIOCONJUGATION OF OLIGONUCLEOTIDES | Proligo L.L.C. (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998030720-A1 | BIOCONJUGATION OF OLIGONUCLEOTIDES | PROLIGO LLC (US) | 1998-07-16 | — | — | WO | disclosed |