Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 6/20 | 0.49 |
| ▸ | CDK1 | P06493 | 5/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.49 |
| ▸ | MGMT | P16455 | 3/20 | 0.49 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559859 | 1.00 | PDPK1 (0.54) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL669641 | 0.83 | PDPK1 (0.53) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL11222102 | 0.81 | PDPK1 (0.63) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL5576430 | 0.81 | CDK2 (0.42) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL6533720 | 0.81 | DPP4 (0.51) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL490904 | 0.80 | PDPK1 (0.50) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL17060283 | 0.80 | PDPK1 (0.61) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL1924592 | 0.78 | PDPK1 (0.59) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL9176120 | 0.78 | PDPK1 (0.59) | PDPK1GDACDK2CDK1CCNB1 | |
| SCHEMBL29592683 | 0.78 | PDPK1 (0.59) | PDPK1GDACDK2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240822-A | Single-base gene editor pBE-C2A-T3 and preparation method and application thereof | 云南师范大学 | 2024-06-25 | — | — | CN | claimed |
| CN-116445463-B | Novel plant base editor pAYBEs | 中国农业科学院作物科学研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-114250272-B | Fluorescent biosensor based on CRISPR and application of fluorescent biosensor in DNA glycosylase detection | 山东师范大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117321218-A | Regeneration method and kit of reusable initiators for nucleic acid synthesis | 陈呈尧 | 2023-12-29 | — | — | CN | claimed |
| CN-116694605-A | Alkyladenine DNA glycosylase mutant, fusion protein and application | 苏州系统医学研究所 | 2023-09-05 | — | — | CN | claimed |
| CN-116445463-A | Novel plant base editor pAYBEs | 中国农业科学院作物科学研究所 | 2023-07-18 | — | — | CN | claimed |
| US-20230212214-A1 | CLEAVABLE DNA-ENCODED LIBRARY | NISSAN CHEMICAL CORPORATION (JP) | 2023-07-06 | — | — | US | claimed |
| CN-112423885-B | Polynucleotide synthesis methods, kits and systems | 牛津纳米孔科技公开有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-111154839-B | Fluorescent chemical sensor for simultaneously detecting multiple DNA glycosylases, detection method and application thereof | 山东师范大学 | 2023-05-02 | — | — | CN | claimed |
| EP-4159766-A1 | CLEAVABLE DNA-ENCODED LIBRARY | Nissan Chemical Corporation (JP) | 2023-04-05 | — | — | EP | claimed |
| WO-2004046324-A2 | ALLELE-TARGETED RNA INTERFERENCE | UNIVERSITY OF MASSACHUSETTS (US) | 2004-06-03 | — | — | WO | claimed |
| US-20040038274-A1 | Gapped 2' modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2004-02-26 | — | — | US | claimed |
| US-20020160379-A1 | Gapped 2' modified oligonucleotides | ISIS PHARMACEUTICALS, INC. | 2002-10-31 | — | — | US | claimed |
| JP-3131222-B2 | — | — | 2001-01-31 | — | — | JP | claimed |
| US-6146829-A | MODIFYING RNA IN TEST SOLUTION CONTAINING RNASE HI BY HYBRIDIZING WITH OLIGONUCLEOTIDE HAVING NUCLEOTIDES WITH 2'DEOXY-ERYTHRO-PENTOFURANOSYL SUGAR MOIETIES; ACTIVATES RNASE AND RESISTS NUCLEASE DEGRADATION | ISIS PHARMACEUTICALS, INC. (US) | 2000-11-14 | — | — | US | claimed |
| EP-1044987-A2 | Gapped 2'-modified oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 2000-10-18 | — | — | EP | claimed |
| US-5623065-A | MODIFIED OLIGONUCLEOTIDE WHICH HAS BINDING AFFINITY TO COMPLEMENTARY NUCLEIC ACID, INHIBITS TRANSLOCATION OF SAID ACID, PROMOTES RIBONUCLEASE CLEAVAGE IN VITRO | ISIS PHARMACEUTICALS, INC. (US) | 1997-04-22 | — | — | US | claimed |
| EP-0618925-A4 | GAPPED 2' MODIFIED OLIGONUCLEOTIDES. | ISIS PHARMACEUTICALS INC (US) | 1997-01-02 | — | — | EP | claimed |
| EP-0618925-A1 | GAPPED 2' MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-12 | — | — | EP | claimed |
| WO-1993013121-A1 | GAPPED 2' MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1993-07-08 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212214-A1 | CLEAVABLE DNA-ENCODED LIBRARY | FEN1, PCNA, UNG | PDPK1 3094/4885GDA 213/4885CDK2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.