Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dinitro Cresol SCHEMBL29430312 | 0.98 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL8873755 | 0.98 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL20734 | 0.98 | GPR35 (1.00) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL11029120 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL7108490 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL1260257 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL711035 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL9640831 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL906844 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 | |
| Dinitro Cresol SCHEMBL6859521 | 0.96 | GPR35 (0.96) | GPR35ALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592084-B1 | Process for producing pyripyropene derivatives and intermediates for the production thereof. | MEIJI SEIKA PHARMA CO LTD (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-8759529-B2 | Process for producing pyripyropene derivatives and intermediates for the production thereof | BASF SE (DE) | 2014-06-24 | — | — | US | disclosed |
| EP-2592084-A1 | Process for producing pyripyropene derivatives and intermediates for the production thereof. | Meiji Seika Pharma Co., Ltd. (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20120330021-A1 | PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVES AND INTERMEDIATES FOR THE PRODUCTION THEREOF | BASF SE (DE) | 2012-12-27 | — | — | US | disclosed |
| US-8263778-B2 | Process for producing pyripyropene derivatives and intermediates for the production thereof | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20100160640-A1 | PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVES AND INTERMEDIATES FOR THE PRODUCTION THEREOF | MEIJI SEIKA KAISHA, LTD. | 2010-06-24 | — | — | US | disclosed |
| EP-2186815-A1 | METHOD FOR PRODUCING PYRIPYROPENE DERIVATIVE AND PRODUCTION INTERMEDIATE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330021-A1 | PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVES AND INTERMEDIATES FOR THE PRODUCTION THEREOF | CYP51A1, POR, COASY | GPR35 2674/4885ALDH1A1 2125/4885KMT2A 2538/4885 |
| US-20100160640-A1 | PROCESS FOR PRODUCING PYRIPYROPENE DERIVATIVES AND INTERMEDIATES FOR THE PRODUCTION THEREOF | PC, CBR3, AKR1C3 | GPR35 1508/4885ALDH1A1 3899/4885KMT2A 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.