SCHEMBL3253191

SCHEMBL3253191

O/N=C(/c1ccccc1)C1CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
RAB9A P51151 1/20 0.42
GAA P10253 5/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.39
ELANE P08246 1/20 0.38
CYP2C19 P33261 1/20 0.38
HRH4 Q9H3N8 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C1 Q04828 1/20 0.34
HPGD P15428 1/20 0.34
GFER P55789 1/20 0.34
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4799721 1.00 MEN1 (0.55) MEN1KMT2ARAB9AGAALMNA
SCHEMBL9189393 1.00 MEN1 (0.55) MEN1KMT2ARAB9AGAALMNA
SCHEMBL5479525 0.91 MEN1 (0.61) MEN1KMT2ARAB9AGAALMNA
SCHEMBL17988346 0.91 MEN1 (0.56) MEN1KMT2ARAB9AGAALMNA
SCHEMBL5479522 0.91 MEN1 (0.61) MEN1KMT2ARAB9AGAALMNA
SCHEMBL182715 0.90 MEN1 (0.54) MEN1KMT2ARAB9AGAALMNA
SCHEMBL10050933 0.90 MEN1 (0.54) MEN1KMT2ARAB9AGAALMNA
SCHEMBL182714 0.90 MEN1 (0.54) MEN1KMT2ARAB9AGAALMNA
SCHEMBL6878397 0.86 MEN1 (0.47) MEN1KMT2ARAB9AGAALMNA
SCHEMBL20385256 0.86 MEN1 (0.47) MEN1KMT2ARAB9AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9411226-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-09 US disclosed
US-9411226-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-09 US disclosed
EP-1769103-B1 ELECTROCHEMICAL PROCESS FOR PREPARING CYCLOPROPYLBENZYLAMINES BASF SE (DE) 2010-05-05 EP disclosed
EP-1769103-B1 ELECTROCHEMICAL PROCESS FOR PREPARING CYCLOPROPYLBENZYLAMINES BASF SE (DE) 2010-05-05 EP disclosed
US-7411094-B2 Method for the production of primary amines comprising a primary amino group which bound to an aliphatic or cycloaliphatic C-atom, and a cyclopropyl unit BASF AKTIENGESELLSCHAFT (DE) 2008-08-12 US disclosed
US-20080064901-A1 Method for the Production of Primary Amines Comprising a Primary Amino Group Which is Bound to an Aliphatic or Cycloaliphatic C-Atom, and a Cyclopropyl Unit BASF (DE) 2008-03-13 US disclosed
EP-1769103-A1 METHOD FOR THE PRODUCTION OF PRIMARY AMINES COMPRISING A PRIMARY AMINO GROUP WHICH IS BOUND TO AN ALIPHATIC OR CYCLOALIPHATIC C-ATOM, AND A CYCLOPROPYL UNIT BASF AKTIENGESELLSCHAFT (DE) 2007-04-04 EP disclosed
WO-2006005531-A1 METHOD FOR THE PRODUCTION OF PRIMARY AMINES COMPRISING A PRIMARY AMINO GROUP WHICH IS BOUND TO AN ALIPHATIC OR CYCLOALIPHATIC C-ATOM, AND A CYCLOPROPYL UNIT BASF AKTIENGESELLSCHAFT (DE) 2006-01-19 WO disclosed
US-5464847-A Moduators of corticotropin releasing factor ELF SANOFI (FR) 1995-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064901-A1 Method for the Production of Primary Amines Comprising a Primary Amino Group Which is Bound to an Aliphatic or Cycloaliphatic C-Atom, and a Cyclopropyl Unit CYCS, DAO, MAOB MEN1 2005/4885KMT2A 881/4885RAB9A 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.