Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050933 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL182714 | 1.00 | MEN1 (0.54) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL17988346 | 0.98 | MEN1 (0.56) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL5479522 | 0.94 | MEN1 (0.61) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL5479525 | 0.94 | MEN1 (0.61) | MEN1KMT2ALMNAGAAPOLB | |
| SCHEMBL3253191 | 0.90 | MEN1 (0.55) | MEN1KMT2ALMNAGAAELANE | |
| SCHEMBL9189393 | 0.90 | MEN1 (0.55) | MEN1KMT2ALMNAGAAELANE | |
| SCHEMBL4799721 | 0.90 | MEN1 (0.55) | MEN1KMT2ALMNAGAAELANE | |
| SCHEMBL11438285 | 0.81 | LMNA (0.54) | MEN1KMT2ALMNAGAARAB9A | |
| SCHEMBL11438283 | 0.81 | LMNA (0.54) | MEN1KMT2ALMNAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | claimed |
| CN-108355709-A | Purposes of the Bismuth triflate as Beckmann rearrangement catalyst | 嘉兴学院 | 2018-08-03 | — | — | CN | claimed |
| CN-106397218-A | S-alpha-cyclohexyl benzene methanamine | 王际菊 | 2017-02-15 | — | — | CN | claimed |
| CN-108355709-B | Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst | 嘉兴学院 | 2020-12-08 | — | — | CN | disclosed |
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2019-01-08 | — | — | US | disclosed |
| CN-108355709-A | Purposes of the Bismuth triflate as Beckmann rearrangement catalyst | 嘉兴学院 | 2018-08-03 | — | — | CN | disclosed |
| CN-104382924-B | N6 substituted adenosines derivative and N6 substituted adenines derivatives and application thereof | 中国医学科学院药物研究所 | 2017-12-22 | — | — | CN | disclosed |
| CN-106397218-A | S-alpha-cyclohexyl benzene methanamine | 王际菊 | 2017-02-15 | — | — | CN | disclosed |
| CN-106397220-A | Method for preparing L-o-tert-butylcyclohexylamine | 陈永军 | 2017-02-15 | — | — | CN | disclosed |
| CN-106381317-A | Preparation method of L-chiral amino compound | 陈永军 | 2017-02-08 | — | — | CN | disclosed |
| CN-102812033-B | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-1956964-B | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV | 2011-06-15 | — | — | CN | disclosed |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | LAGU BHARAT | 2009-04-16 | — | — | US | disclosed |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | LAGU BHARAT | 2009-04-16 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| US-7452997-B2 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-11-18 | — | — | US | disclosed |
| CN-1956964-A | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2007-05-02 | — | — | CN | disclosed |
| EP-1735286-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-27 | — | — | EP | disclosed |
| US-20050228034-A1 | Tetrahydro-indazole cannabinoid modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-10-13 | — | — | US | disclosed |
| WO-2005095353-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228034-A1 | Tetrahydro-indazole cannabinoid modulators | CNR2, CNR1, GPR18 | MEN1 3259/4885KMT2A 2618/4885LMNA 4334/4885 |
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | ADORA2A, ADORA3, ADORA1 | MEN1 2341/4885KMT2A 373/4885LMNA 812/4885 |
| US-20090099143-A1 | TETRAHYDRO-INDAZOLE CANNABINOID MODULATORS | CNR2, CNR1, GPR18 | MEN1 3259/4885KMT2A 2618/4885LMNA 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.