⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6752536 | 0.81 | APP (0.35) | — | |
| SCHEMBL4562631 | 0.79 | KCNH2 (0.67) | — | |
| SCHEMBL30707869 | 0.79 | KCNH2 (0.67) | — | |
| SCHEMBL2862005 | 0.79 | KCNH2 (0.50) | — | |
| Charcoal, Activated SCHEMBL31286308 | 0.77 | KCNH2 (0.64) | — | |
| SCHEMBL98355 | 0.75 | — | — | |
| SCHEMBL29666129 | 0.75 | — | — | |
| SCHEMBL16618655 | 0.75 | — | — | |
| SCHEMBL30230632 | 0.75 | — | — | |
| SCHEMBL560108 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200905-A | Chiral indolone derivative and synthesis method thereof | 中山大学 | 2021-08-03 | — | — | CN | claimed |
| CN-112047981-B | Temperature-controlled intelligent vapor luminescent switch material, preparation method and application thereof | 大连理工大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112047981-A | Temperature-controlled intelligent vapor luminescent switch material, preparation method and application thereof | 大连理工大学 | 2020-12-08 | — | — | CN | claimed |
| EP-3400220-A1 | PYRAZOLE DERIVATIVES | Hua Medicine (Shanghai) Ltd. (CN) | 2018-11-14 | — | — | EP | claimed |
| US-20180020662-A1 | Substituted 1-cycloalkyl-2-oxotetrahydroquinolin-6-ylsulfonamides or salts thereof and use thereof to increase stress tolerance in plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-25 | — | — | US | claimed |
| EP-3256448-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-12-20 | — | — | EP | claimed |
| WO-2017117708-A1 | PYRAZOLE DERIVATIVES | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2017-07-13 | — | — | WO | claimed |
| WO-2016128365-A1 | SUBSTITUTED 1-CYCLOALKYL-2-OXOTETRAHYDROQUINOLIN-6-YL-SULFONAMIDES OR SALTS THEREOF AND USE THEREOF TO INCREASE STRESS TOLERANCE IN PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | WO | claimed |
| EP-1599201-B1 | SELECTIVE NON-STEROIDAL GLUCOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2010-04-14 | — | — | EP | claimed |
| US-7411073-B2 | Selective non-steroidal glucocorticoid receptor modulators | MERCK & CO., INC. (US) | 2008-08-12 | — | — | US | claimed |
| US-20060074120-A1 | cyclopent[f]pyrazole derivatives; antiinflammatory agent; autoimmune diseases; side effect reduction, advantages over steroidal glucocorticoid ligands with respect to undesireable side-effects, efficacy, toxicity or metabolism | MERCK SHARP & DOHME CORP. | 2006-04-06 | — | — | US | claimed |
| EP-4379888-A1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY PROVIDED WITH SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2024-06-05 | — | — | EP | disclosed |
| CN-117795727-A | Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery provided with same | 信越化学工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| WO-2023008030-A1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY PROVIDED WITH SAME | 信越化学工業株式会社 | 2023-02-02 | — | — | WO | disclosed |
| CN-113200905-B | Chiral indolone derivative and synthesis method thereof | 中山大学 | 2022-12-27 | — | — | CN | disclosed |
| US-6855722-B2 | Substituted indoles and their use as integrin antagonists | DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-02-15 | — | — | US | disclosed |
| EP-1425010-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2004-06-09 | — | — | EP | disclosed |
| US-20020169200-A1 | Substituted indoles and their use as integrin antagonists | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2002-11-14 | — | — | US | disclosed |
| WO-2002060438-A1 | SUBSTITUTED INDOLES AND THEIR USE AS INTEGRIN ANTAGONISTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| US-4517197-A | ANTIDEPRESSANTS | DELALANDE S.A. (FR) | 1985-05-14 | — | — | US | disclosed |