⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222138 | 1.00 | — | — | |
| SCHEMBL28783597 | 0.87 | ALDH1A1 (0.35) | — | |
| SCHEMBL251689 | 0.82 | — | — | |
| SCHEMBL289603 | 0.82 | — | — | |
| SCHEMBL861285 | 0.82 | — | — | |
| SCHEMBL1147856 | 0.82 | — | — | |
| SCHEMBL3263623 | 0.82 | — | — | |
| SCHEMBL1627426 | 0.82 | — | — | |
| SCHEMBL8085351 | 0.82 | — | — | |
| SCHEMBL8517756 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1387660-B1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2010-07-14 | — | — | EP | disclosed |
| EP-1387660-A4 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2006-05-17 | — | — | EP | disclosed |
| CN-1711069-A | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2005-12-21 | — | — | CN | disclosed |
| US-6762164-B2 | HAIR GROWTH PROMOTING AGENT INCLUDING A CYCLOSPORIN DERIVATIVE AS AN ACTIVE INGREDIENT, AND MORE PARTICULARLY, A HAIR GROWTH PROMOTING AGENT INCLUDING A CYCLOSPORIN A DERIVATIVE SUBSTITUTED IN THE 3-POSITION AS AN ACTIVE INGREDIENT. | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-07-13 | — | — | US | disclosed |
| CN-1507339-A | Use of 3-position cyclosporin derivatives for hair growth | LG HOUSEHOLD & HEALTH CARE LTD (KR) | 2004-06-23 | — | — | CN | disclosed |
| EP-1392224-A1 | THE USE OF NONIMMUNOSUPPRESSIVE EPSILON-HYDROXY-N-METHYL-L-LEUCINE-4 ] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG Household & Health Care Ltd. (KR) | 2004-03-03 | — | — | EP | disclosed |
| EP-1387660-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG Household & Health Care Ltd. (KR) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002092033-A1 | THE USE OF NONIMMUNOSUPPRESSIVE [$G(G)-HYDROXY-N-METHYL-L-LEUCINE4] CYCLOSPORIN DERIVATIVES FOR TREATING HAIR LOSS | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092032-A1 | USE OF 3-POSITION CYCLOSPORIN DERIVATIVES FOR HAIR GROWTH | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2002-11-21 | — | — | WO | disclosed |
| EP-0345728-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-09-14 | — | — | EP | disclosed |
| EP-0299497-B1 | Dye composition for keratinous fiber | KAO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| EP-0376078-A2 | Dye composition for keratinous fiber | KAO CORPORATION (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0345728-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-12-13 | — | — | EP | disclosed |