SCHEMBL3254446

SCHEMBL3254446

NN1Cc2cc(C(F)(F)C(F)(F)F)ccc2NC1=O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 10/20 0.38
KIF11 P52732 4/20 0.38
TDP2 O95551 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
AADAT Q8N5Z0 1/20 0.33
PKM P14618 1/20 0.32
PKLR P30613 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28346622 0.88 BRD4 (0.38) BRD4KIF11TDP2KMT2AGAA
SCHEMBL30912755 0.76 HTR5A (0.46) BRD4KMT2A
SCHEMBL3252900 0.75 CES1 (0.51) BRD4KIF11
SCHEMBL3248383 0.73 BRD4 (0.41) BRD4GAA
SCHEMBL11803041 0.72
SCHEMBL27394981 0.70 BRD4 (0.62) BRD4KIF11
SCHEMBL27997052 0.69 BRD4 (0.45) BRD4KIF11KMT2AGAAPKM
SCHEMBL7083744 0.69 BRD4 (0.61) BRD4KMT2A
SCHEMBL28347259 0.66
SCHEMBL27480151 0.66 GAA (0.45) BRD4KIF11TDP2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1097932-B1 Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same NIHON NOHYAKU CO LTD (JP) 2010-02-10 EP disclosed
US-6455535-B1 INSECTICIDES NIHON NOHYAKU CO., LTD. (JP) 2002-09-24 US disclosed
EP-1097932-A1 Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same NIHON NOHYAKU CO., LTD. (JP) 2001-05-09 EP disclosed