⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9330835 | 0.97 | LMNA (0.47) | — | |
| SCHEMBL12204384 | 0.82 | ADRB2 (0.45) | — | |
| SCHEMBL12204382 | 0.82 | ADRB2 (0.45) | — | |
| SCHEMBL12130687 | 0.82 | HDAC4 (0.38) | — | |
| SCHEMBL717099 | 0.73 | EGLN1 (0.34) | — | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.71 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.71 | — | — | |
| SCHEMBL12446580 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL29957252 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL12789152 | 0.69 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778210-B | Synthetic method of 3-selenoindole compound | 苏州大学 | 2020-04-10 | — | — | CN | claimed |
| US-11912786-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-27 | — | — | US | disclosed |
| US-11647671-B2 | Compound and organic electro-optical device containing the same | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-05-09 | — | — | US | disclosed |
| CN-115322192-A | Pyrrolo [3,4-b ] pyridine derivatives, and synthesis method and application thereof | 重庆文理学院 | 2022-11-11 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114591212-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112824438-B | Synthetic method of polyimide | 湘潭大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |
| US-11111270-B2 | Inhibitor of apoptosis protein (IAP) antagonists | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-09-07 | — | — | US | disclosed |
| CN-112824438-A | Novel synthesis method of polyimide | 湘潭大学 | 2021-05-21 | — | — | CN | disclosed |
| WO-2007100657-A2 | INHIBITORS OF HISTONE DEACETYLASE | MERCK & CO., INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-7247731-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-24 | — | — | US | disclosed |
| US-20070149535-A1 | Protein kinase inhibitors | ONCALIS AG (CH) | 2007-06-28 | — | — | US | disclosed |
| US-20070123707-A1 | Nitrogen-containing monodentate phosphines and their use in catalysis | DEGUSSA AG (DE) | 2007-05-31 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
| US-20070021611-A1 | Pyridyl and phenyl substituted piperazine-piperidines with CXCR3 antagonist activity | SCHERING CORPORATION | 2007-01-25 | — | — | US | disclosed |
| WO-2006067462-A1 | 1,6 - SUBSTITUTED (3R,6R) -3- (2,3-DIHYDRO-1H-INDEN-2-YL)-2,5-PIPERAZINEDIONE DERIVATIVES AS OXYTOCIN RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PRE-TERM LABOUR, DYSMENORRHEA AND ENDOMETRIOSIS | GLAXO GROUP LIMITED (GB) | 2006-06-29 | — | — | WO | disclosed |
| EP-0947561-B1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-6235861-B1 | REACTION INHIBITOR IS ADDED TO THE COMPOSITION COMPRISING AN ALKENYLATED ORGANOPOLYSILOXANE, AN ORGANOHYDROGENPOLYSILOXANE, AND A PLATINUM CATALYST. | THREE BOND (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0947561-A1 | ORGANOPOLYSILOXANE COMPOSITION | THREE BOND CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |