SCHEMBL325463

SCHEMBL325463

C=CCc1cc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.58
IDO1 P14902 2/20 0.51
HRH3 Q9Y5N1 1/20 0.46
AHR P35869 1/20 0.46
HRH4 Q9H3N8 1/20 0.45
CYP2A6 P11509 1/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
AOC3 Q16853 2/20 0.44
PCSK9 Q8NBP7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31105584 1.00 LOXL2 (0.58) LOXL2IDO1HRH3AHRHRH4
SCHEMBL28876221 0.98 LOXL2 (0.56) LOXL2IDO1HRH3AHRHRH4
SCHEMBL28876206 0.98 LOXL2 (0.56) LOXL2IDO1HRH3AHRHRH4
Bromide SCHEMBL27641073 0.98 LOXL2 (0.56) LOXL2IDO1HRH3AHRHRH4
Ammonia Solution, Strong SCHEMBL28873731 0.98 LOXL2 (0.56) LOXL2IDO1HRH3AHRHRH4
SCHEMBL28346906 0.86 LOXL2 (0.45) LOXL2IDO1HRH3AHRHRH4
SCHEMBL5642064 0.82 LOXL2 (0.60) LOXL2IDO1HRH3AHRHRH4
SCHEMBL2592547 0.82 LOXL2 (0.60) LOXL2IDO1HRH3AHRHRH4
SCHEMBL6156791 0.81 LOXL2 (0.55) LOXL2IDO1HRH3AHRHRH4
SCHEMBL6254747 0.81 LOXL2 (0.55) LOXL2IDO1HRH3AHRHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 504 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025000181-A1 GOSSYPOL-CONTAINING STEM BORER-KILLING COMPOSITION 山东省农业科学院 2025-01-02 WO claimed
CN-118421189-A Piezoelectric allyl ester indole antifouling paint and preparation method and application thereof 武汉理工大学三亚科教创新园 2024-08-02 CN claimed
CN-117186089-A Preparation method of tetrahydrocarboline derivative 浙江大学 2023-12-08 CN claimed
CN-115772111-A Alkyl indole polyether carboxylate surfactant and preparation method and application thereof 中国石油化工股份有限公司 2023-03-10 CN claimed
CN-115108532-B Magnesium-based hydrogen storage material and preparation method thereof 苏州清德氢能源科技有限公司 2022-11-15 CN claimed
CN-115108532-A Magnesium-based hydrogen storage material and preparation method thereof 苏州清德氢能源科技有限公司 2022-09-27 CN claimed
CN-115043899-A Diamine or compound coupling diamine and thiol as well as preparation method and application thereof 南开大学 2022-09-13 CN claimed
CN-108912036-B Method for preparing allylindole compound by alkene 1, 4-bifunctional reaction 南昌航空大学 2021-06-25 CN claimed
EP-3138890-B1 AGGREGATING COMPOSITIONS, MODIFIED PARTICULATE METAL OXIDES, MODIFIED FORMATION SURFACES, AND METHODS FOR MAKING AND USING SAME LUBRIZOL CORP (US) 2020-11-11 EP claimed
EP-3071666-B1 METHOD AND COMPOSITION FOR CONSOLIDATING SOLID MATERIALS DURING SUBTERRANEAN TREATMENT OPERATIONS LUBRIZOL CORP (US) 2020-08-12 EP claimed
EP-0758893-A1 POTENTIATED ANTIBIOTIC COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-02-26 EP claimed
WO-1995030417-A1 POTENTIATED ANTIBIOTIC COMPOSITION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-11-16 WO claimed
US-5229375-A PHOSPHENE OXIDE-TERMINATED ALLENE-ENE-YNE DNA-CLEAVING, ANTITUMOR AND ANTIBIOTIC MOLECULES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1993-07-20 US claimed
EP-0541670-A4 PHOSPHENE OXIDE-TERMINATED ALLENE-ENE-YNE DNA-CLEAVING, ANTITUMOR AND ANTIBIOTIC MOLECULES 1993-06-16 EP claimed
EP-0541670-A1 PHOSPHENE OXIDE-TERMINATED ALLENE-ENE-YNE DNA-CLEAVING, ANTITUMOR AND ANTIBIOTIC MOLECULES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1993-05-19 EP claimed
WO-1992002227-A1 PHOSPHENE OXIDE-TERMINATED ALLENE-ENE-YNE DNA-CLEAVING, ANTITUMOR AND ANTIBIOTIC MOLECULES SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1992-02-20 WO claimed
CN-1042553-A The preparation method of indigo compound MITSUI TOATSU CHEMICALS (JP) 1990-05-30 CN claimed
CN-1036025-A The preparation method of indigo compound MITSUI TOATSU CHEMICALS (JP) 1989-10-04 CN claimed
CN-1035521-A The preparation method of indigo compound MITSUI TOATSU CHEMICALS (JP) 1989-09-13 CN claimed
US-4374846-A N-Amino alkyl indole compounds compositions containing same, and a method of using same in therapy of disorders of gastrointestinal motility KALI-CHEMIE PHARMA GMBH (DE) 1983-02-22 US claimed