Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5642064 | 0.84 | LOXL2 (0.60) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL5641541 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL29796415 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL1327113 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL325463 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL108898 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL653529 | 0.82 | LOXL2 (0.63) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL2485760 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL31105584 | 0.82 | LOXL2 (0.58) | LOXL2HRH3AHRHRH4CYP2A6 | |
| SCHEMBL28876206 | 0.81 | LOXL2 (0.56) | LOXL2HRH3AHRHRH4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011139242-A2 | PROCESS FOR THE PREPARATION OF 2,3,4,5-TETRAHYDRO-1H-PYRIDO[4,3-B]INDOLE DERIVATIVES | USTAV EXPIREMENTÁLNEJ FARMAKOLÓGIE A TOXIKOLÓGIE SAV (SK) | 2011-11-10 | — | — | WO | disclosed |