Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005783 | 0.81 | TSHR (0.57) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL4631197 | 0.80 | TSHR (0.50) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL1425850 | 0.77 | TSHR (0.52) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL10973052 | 0.77 | TSHR (0.52) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL214681 | 0.77 | TSHR (0.52) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL29169702 | 0.77 | TSHR (0.52) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL4767507 | 0.77 | TSHR (0.52) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL6598540 | 0.75 | TSHR (0.50) | TSHRIDO1AGXTRAB9ANPC1 | |
| SCHEMBL5229035 | 0.75 | AGXT (0.54) | IDO1AGXTRAB9ANPC1CA1 | |
| SCHEMBL17986230 | 0.75 | IDO1 (0.54) | IDO1AGXTRAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | SINDKHEDKAR MILIND D | 2009-01-15 | — | — | US | claimed |
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | BAYER CROPSCIENCE AG (DE) | 2008-11-27 | — | — | US | claimed |
| EP-1912980-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | Wockhardt Limited (IN) | 2008-04-23 | — | — | EP | claimed |
| WO-2007023507-A2 | OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION | WOCKHARDT LIMITED (IN) | 2007-03-01 | — | — | WO | claimed |
| EP-1751152-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | Bayer CropScience Aktiengesellschaft (DE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113553-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | claimed |
| WO-2005041665-A1 | INSECTICIDAL PERFLUOROALKYLTHIAZOLE DERIVATIVES | NIPPON SODA CO. LTD. (JP) | 2005-05-12 | — | — | WO | claimed |
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | NIPPON SODA CO., LTD. | 2005-04-28 | — | — | US | claimed |
| EP-0349282-B1 | 2-(Acylimino)thiazolidine Herbicides | ICI AMERICA INC (US) | 1994-08-17 | — | — | EP | claimed |
| EP-0451168-B1 | 1-PHENYL-3-CARBOXYAMIDOPYRROLIDONES AND THEIR USE AS HERBICIDES | ZENECA INC (US) | 1994-06-15 | — | — | EP | claimed |
| EP-0377532-A1 | Thioformamide derivatives | MAY AND BAKER LIMITED (GB) | 1990-07-11 | — | — | EP | claimed |
| US-4913722-A | HERBICIDES | ICI AMERICAS INC. (US) | 1990-04-03 | — | — | US | claimed |
| EP-0349282-A1 | 2-(Acylimino)thiazolidine Herbicides | ZENECA INC. (US) | 1990-01-03 | — | — | EP | claimed |
| EP-0349283-A1 | Novel herbicidal 2-sulfonyliminothiazolidines | ZENECA INC. (US) | 1990-01-03 | — | — | EP | claimed |
| US-4877880-A | REACTING AN N-3-SUBSTITUTED ALLYL ANILINE WITH AN ARYLISOTHIOCYANATE, REACTING THE RESULTANT THIOUREA WITH A (TRIFLUORO-)METHANESULFONIC ACID | ICI AMERICAS INC. (US) | 1989-10-31 | — | — | US | claimed |
| US-4874422-A | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides | ICI AMERICAS INC. (US) | 1989-10-17 | — | — | US | claimed |
| US-4867780-A | PRE- AND POSTEMERGENCE HERBICIDES | ICI AMERICAS, INC. (US) | 1989-09-19 | — | — | US | claimed |
| US-4867782-A | BROADLEAF AND GRASSY WEEDS | ICI AMERICAS INC. (US) | 1989-09-19 | — | — | US | claimed |
| EP-0318253-A1 | Iminophenylthiazolidines, process of preparation, and method of use | ICI AMERICAS INC. (US) | 1989-05-31 | — | — | EP | claimed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293674-A1 | Azinyl Imidazoazine and Azinyl Carboxamide | AZI2, NISCH, ZYX | TSHR 3493/4885IDO1 93/4885AGXT 2744/4885 |
| US-20050090506-A1 | Insecticidal perfluoroalkylthiazole derivatives | FFAR3, CYP4F3, NPFFR1 | TSHR 113/4885IDO1 3341/4885AGXT 1406/4885 |
| US-20090018123-A1 | Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation | POLL, POLM, POLRMT | TSHR 3584/4885IDO1 3719/4885AGXT 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.