Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylbenzene SCHEMBL2121105 | 0.90 | TP53 (0.52) | TP53SIGMAR1MEN1KMT2AALDH1A1 | |
| Ethylbenzene SCHEMBL10489218 | 0.88 | TP53 (0.74) | TP53RAB9AKDM4ENPC1POLB | |
| Tetrahydrofuran SCHEMBL28900801 | 0.88 | TP53 (0.48) | TP53RAB9AKDM4ENPC1 | |
| Ethylbenzene SCHEMBL11783786 | 0.86 | TP53 (0.47) | TP53RAB9AKDM4ENPC1FKBP1A | |
| Ethylbenzene SCHEMBL11052893 | 0.83 | TP53 (0.82) | TP53RAB9AKDM4ENPC1POLB | |
| Ethylbenzene SCHEMBL7902673 | 0.83 | TP53 (0.82) | TP53RAB9AKDM4ENPC1POLB | |
| Ethylbenzene SCHEMBL28826931 | 0.83 | TP53 (0.82) | TP53RAB9AKDM4ENPC1POLB | |
| Ethylbenzene SCHEMBL27294466 | 0.83 | — | — | |
| Tetrahydrofuran SCHEMBL8893050 | 0.81 | SIGMAR1 (0.52) | NPC1FKBP1APOLBSIGMAR1LMNA | |
| Ethylbenzene SCHEMBL11223212 | 0.80 | TP53 (1.00) | TP53RAB9AKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106938981-A | A kind of preparation method of NVP intermediate sphaerocrystal | 浙江华海药业股份有限公司 | 2017-07-11 | — | — | CN | claimed |
| EP-0870777-B1 | Initiator system and process for the anionic (co)polymerisation of (meth)acrylic, vinylaromatic and/or dienic monomers | ATOFINA (FR) | 2003-09-24 | — | — | EP | claimed |
| EP-0870775-B1 | Initiator system comprising a silyl initiator for the anionic (co)polymerisation of (meth)acrylic monomers and process using it | ATOFINA (FR) | 2002-12-11 | — | — | EP | claimed |
| US-20010018397-A1 | Comprising reaction product of a cyclic siloxane and an organometallic compound such as sec-butyllithium; for making polymethyl methacrylate with high content of isotactic triads | ELF ATOCHEM S.A. (FR) | 2001-08-30 | — | — | US | claimed |
| US-20010003726-A1 | INITIATION SYSTEM COMPRISING AN AMINO ALCOHOLATE LIGAND FOR ANIONIC COPOLYMERIZATION OF (METH)ACRYLIC MONOMERS AND PROCESS USING SAME | ELF ATOCHEM S.A. (FR) | 2001-06-14 | — | — | US | claimed |
| US-10374175-B2 | Platinum complex compound and organic electroluminescence device using the same | UDC IRELAND LIMITED (IE) | 2019-08-06 | — | — | US | disclosed |
| CN-106938981-A | A kind of preparation method of NVP intermediate sphaerocrystal | 浙江华海药业股份有限公司 | 2017-07-11 | — | — | CN | disclosed |
| CN-103974929-B | The manufacture method of the halogen acid salt of haloalkylamine | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| US-20160099426-A1 | Platinum Complex Compound And Organic Electroluminescence Device Using The Same | UDC Ireland (IE) | 2016-04-07 | — | — | US | disclosed |
| EP-2070936-B1 | Platinum complex compound and organic electroluminescence device using the same | FUJIFILM CORP (JP) | 2010-05-26 | — | — | EP | disclosed |
| EP-2070936-A1 | Platinum complex compound and organic electroluminescence device using the same | Fujifilm Corporation (JP) | 2009-06-17 | — | — | EP | disclosed |
| EP-1323711-B1 | NOVEL PHENYLALANINE DERIVATIVES | AJINOMOTO KK (JP) | 2006-11-15 | — | — | EP | disclosed |
| EP-1323711-A1 | NOVEL PHENYLALANINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6489262-B2 | COMPRISING REACTION PRODUCT OF A CYCLIC SILOXANE AND AN ORGANOMETALLIC COMPOUND SUCH AS SEC-BUTYLLITHIUM; FOR MAKING POLYMETHYL METHACRYLATE WITH HIGH CONTENT OF ISOTACTIC TRIADS | ATOFINA (FR) | 2002-12-03 | — | — | US | disclosed |
| US-6337297-B1 | CHROMIUM CATALYST FOR TRIMERIZATION OF ETHYLENE WITH MULTIDENTATE LIGAND OR HALOGEN, CARBOXY GROUP | TOSOH CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6319875-B1 | AS ACTIVATOR TO PRODUCE SYNDIOTACTIC ACRYLIC POLYMER | ELF ATOCHEM S.A. (FR) | 2001-11-20 | — | — | US | disclosed |
| US-20010018397-A1 | Comprising reaction product of a cyclic siloxane and an organometallic compound such as sec-butyllithium; for making polymethyl methacrylate with high content of isotactic triads | ELF ATOCHEM S.A. (FR) | 2001-08-30 | — | — | US | disclosed |
| US-6262204-B1 | AS POLYMERIZATION INITIATOR FOR POLYMERIZATION OF (METH)ACRYLIC MONOMERS AND OPTIONALLY ETHYLENICALLY UNSATURATED MONOMERS | ATOFINA (FR) | 2001-07-17 | — | — | US | disclosed |
| US-20010003726-A1 | INITIATION SYSTEM COMPRISING AN AMINO ALCOHOLATE LIGAND FOR ANIONIC COPOLYMERIZATION OF (METH)ACRYLIC MONOMERS AND PROCESS USING SAME | ELF ATOCHEM S.A. (FR) | 2001-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160099426-A1 | Platinum Complex Compound And Organic Electroluminescence Device Using The Same | PARP1, OXA1L, H1-2 | TP53 1404/4885RAB9A 2474/4885KDM4E 3402/4885 |
| US-10374175-B2 | Platinum complex compound and organic electroluminescence device using the same | PARP1, OXA1L, H1-2 | TP53 1404/4885RAB9A 2474/4885KDM4E 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.