Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254955 | 0.84 | LMNA (0.40) | LMNAGABRR1AGBL2GABRPGABRD | |
| SCHEMBL4923299 | 0.78 | — | — | |
| SCHEMBL4925835 | 0.75 | HCAR2 (0.33) | — | |
| SCHEMBL479506 | 0.71 | LMNA (0.46) | LMNAGABRR1AGBL2GABRPGABRD | |
| SCHEMBL4922463 | 0.69 | — | — | |
| SCHEMBL4932404 | 0.68 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL12590748 | 0.67 | AKR1B1 (0.40) | LMNAGABRR1GABRPGABRDGABRA1 | |
| SCHEMBL9918631 | 0.66 | CCR4 (0.44) | CYP1A2CYP2C19 | |
| SCHEMBL4930122 | 0.66 | YTHDC1 (0.43) | HSD17B10 | |
| SCHEMBL24262375 | 0.66 | NOTUM (0.57) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232157-B1 | NON-AGGREGATING, NON-QUENCHING OLIGOMERS COMPRISING NUCLEOTIDE ANALOGUES; METHODS OF SYNTHESIS AND USE THEREOF | EPOCH BIOSCIENCES INC (US) | 2010-05-05 | — | — | EP | disclosed |
| US-6660845-B1 | Peptide nucleic acids in which one or more purine bases are substituted by a pyrazolo(5,4-d)pyrimidine or by a 7-deazapurine purine analogue; improved hybridization analysis | EPOCH BIOSCIENCES, INC. | 2003-12-09 | — | — | US | disclosed |
| EP-1232157-A2 | NON-AGGREGATING, NON-QUENCHING OLIGOMERS COMPRISING NUCLEOTIDE ANALOGUES; METHODS OF SYNTHESIS AND USE THEREOF | Epoch Biosciences, Inc. (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001038584-A2 | NON-AGGREGATING, NON-QUENCHING OLIGOMERS COMPRISING NUCLEOTIDE ANALOGUES; METHODS OF SYNTHESIS AND USE THEREOF | EPOCH BIOSCIENCES, INC. (US) | 2001-05-31 | — | — | WO | disclosed |