Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 3/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 3/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 3/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 3/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 3/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256687 | 0.99 | HTR6 (0.44) | HTR6MEN1RAD52KMT2ACYP19A1 | |
| SCHEMBL3248439 | 0.81 | HTR6 (0.51) | HTR6MEN1RAD52KMT2ACYP19A1 | |
| SCHEMBL4431649 | 0.80 | HTR6 (0.52) | HTR6CYP19A1CACNB4CACNA1ACACNA1G | |
| SCHEMBL5231031 | 0.78 | HTR6 (0.57) | HTR6CYP2D6CYP2C19 | |
| SCHEMBL4553448 | 0.77 | HTR6 (0.42) | HTR6MEN1RAD52KMT2ACYP19A1 | |
| SCHEMBL3257361 | 0.72 | HTR6 (0.65) | HTR6L3MBTL1ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL3251276 | 0.70 | HTR6 (0.66) | HTR6CYP19A1L3MBTL1TSHRCNR2 | |
| SCHEMBL7357652 | 0.69 | NPSR1 (0.39) | MEN1RAD52KMT2AL3MBTL1TSHR | |
| SCHEMBL5227156 | 0.69 | HTR6 (0.48) | HTR6CYP2D6CYP2C19 | |
| SCHEMBL19396331 | 0.67 | HTR6 (0.57) | HTR6CACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537113-B9 | ARYLALKYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2010-05-26 | — | — | EP | disclosed |
| EP-1537113-B1 | ARYLALKYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2009-10-07 | — | — | EP | disclosed |