Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325582 | 1.00 | S1PR2 (0.45) | S1PR2S1PR1CA2ALDH1A1TDP1 | |
| SCHEMBL27581282 | 0.95 | GPR84 (0.49) | S1PR2S1PR1CA2ALDH1A1TDP1 | |
| SCHEMBL27623727 | 0.93 | GPR84 (0.51) | S1PR2S1PR1ALDH1A1SLC1A2SLC1A1 | |
| SCHEMBL27487298 | 0.93 | GPR84 (0.51) | S1PR2S1PR1ALDH1A1SLC1A2SLC1A1 | |
| SCHEMBL325890 | 0.89 | ALDH1A1 (0.42) | S1PR2S1PR1ALDH1A1TDP1SLC1A2 | |
| SCHEMBL325889 | 0.89 | ALDH1A1 (0.42) | S1PR2S1PR1ALDH1A1TDP1SLC1A2 | |
| SCHEMBL326176 | 0.85 | CACNA2D1 (0.42) | S1PR2S1PR1ALDH1A1TDP1SLC1A2 | |
| SCHEMBL5496400 | 0.81 | S1PR2 (0.57) | S1PR2S1PR1CA2ALDH1A1SLC1A2 | |
| SCHEMBL6466558 | 0.81 | S1PR2 (0.57) | S1PR2S1PR1CA2ALDH1A1SLC1A2 | |
| SCHEMBL9176596 | 0.81 | ALDH1A1 (0.54) | CA2ALDH1A1TDP1GPR84MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791108-A1 | SULFONAMIDE DERIVATIVES | Pfizer Limited (GB) | 2014-10-22 | — | — | EP | disclosed |
| EP-2731959-A1 | ENKEPHALIN ANALOGUES | Pfizer Limited (GB) | 2014-05-21 | — | — | EP | disclosed |
| WO-2013088315-A1 | SULFONAMIDE DERIVATIVES | PFIZER LIMITED (GB) | 2013-06-20 | — | — | WO | disclosed |
| EP-2593431-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| EP-2590972-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2013008123-A1 | ENKEPHALIN ANALOGUES | PFIZER LIMITED (GB) | 2013-01-17 | — | — | WO | disclosed |
| WO-2012007869-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012004706-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |
| WO-2010018484-A1 | NEW USES OF DIISOPROPYLAMINE DERIVATIVES | PFIZER LIMITED (GB) | 2010-02-18 | — | — | WO | disclosed |