Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051077 | 0.94 | EPHX1 (0.70) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2446111 | 0.86 | EPHX1 (0.77) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10077312 | 0.85 | CNR1 (0.70) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8338635 | 0.85 | EPHX1 (0.63) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL321835 | 0.85 | MAOA (0.58) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL19420655 | 0.84 | EPHX1 (0.83) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9547553 | 0.84 | EPHX1 (0.83) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3513673 | 0.84 | EPHX1 (0.64) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2894033 | 0.84 | EPHX1 (0.64) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28269720 | 0.83 | EPHX1 (0.58) | EPHX1KDM4EALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590937-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | The University Of Nottingham (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004549-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2012-01-12 | — | — | WO | disclosed |