Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | CDK9 | P50750 | 1/20 | 0.61 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051077 | 0.90 | EPHX1 (0.70) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL21583073 | 0.90 | KDM4E (0.60) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3065011 | 0.89 | EPHX1 (0.70) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL12661777 | 0.87 | EPHX1 (0.71) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL2446111 | 0.86 | EPHX1 (0.77) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL15741133 | 0.85 | EPHX1 (0.73) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3513673 | 0.84 | EPHX1 (0.64) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL325607 | 0.84 | EPHX1 (0.64) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL9547553 | 0.84 | EPHX1 (0.83) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL19420655 | 0.84 | EPHX1 (0.83) | EPHX1KDM4EHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511730-B8 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2009-04-08 | — | — | EP | claimed |
| US-20060128734-A1 | Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases | FLOERSHEIMER ANDREAS | 2006-06-15 | — | — | US | claimed |
| EP-1511730-A2 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | Novartis AG (CH) | 2005-03-09 | — | — | EP | claimed |
| WO-2003099771-A2 | DIARYL UREA DERIVATIVES USEFUL FOR THE TREATMENT OF PROTEIN KINASE DEPENDENT DISEASES | NOVARTIS AG (CH) | 2003-12-04 | — | — | WO | claimed |
| US-12351542-B2 | Spacered urea (meth)acrylates | EVONIK OPERATIONS GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| US-12338202-B2 | One pot synthesis of urea (meth)acrylates | EVONIK OPERATIONS GMBH (DE) | 2025-06-24 | — | — | US | disclosed |
| EP-4148041-B1 | SPACERED UREA (METH)ACRYLATES | EVONIK OPERATIONS GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| EP-4148040-B1 | ONE POT SYNTHESIS OF UREA (METH)ACRYLATES | EVONIK OPERATIONS GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| EP-4148040-B1 | ONE POT SYNTHESIS OF UREA (METH)ACRYLATES | EVONIK OPERATIONS GMBH (DE) | 2023-11-01 | — | — | EP | disclosed |
| US-20230101100-A1 | One Pot Synthesis of Urea (Meth)Acrylates | EVONIK OPERATIONS GMBH (DE) | 2023-03-30 | — | — | US | disclosed |
| US-20230088931-A1 | Spacered Urea (Meth)Acrylates | EVONIK OPERATIONS GMBH (DE) | 2023-03-23 | — | — | US | disclosed |
| EP-4148040-A1 | ONE POT SYNTHESIS OF UREA (METH)ACRYLATES | Evonik Operations GmbH (DE) | 2023-03-15 | — | — | EP | disclosed |
| CN-1301699-A | New direct chain or cyclic urea, its preparing method and medicinal composition containing them | ADIR (FR) | 2001-07-04 | — | — | CN | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4918091-A | HYPERGLYCEMIC, ANTILIPEMIC AGENTS | BEECHAM GROUP P.L.C. (GB) | 1990-04-17 | — | — | US | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0295828-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4435567-A | REACTING AN AMINE WITH AN N-CARBAMOYL BENZOIC ACID SULFIMIDE | CHINOIN GYOGYSZER ES VESGYESZETI TERMEKEK GYARA R. T. (HU) | 1984-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351542-B2 | Spacered urea (meth)acrylates | METTL14, METTL3, FUS | EPHX1 3389/4885KDM4E 821/4885HTT 323/4885 |
| US-12338202-B2 | One pot synthesis of urea (meth)acrylates | ADH1A, ADH1C, METTL14 | EPHX1 2807/4885KDM4E 1350/4885HTT 62/4885 |
| US-20230101100-A1 | One Pot Synthesis of Urea (Meth)Acrylates | ADH1A, ADH1C, METTL14 | EPHX1 2807/4885KDM4E 1350/4885HTT 62/4885 |
| US-20060128734-A1 | Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases | UCK2, PRKDC, PRKACA | EPHX1 2991/4885KDM4E 1003/4885HTT 2115/4885 |
| US-20230088931-A1 | Spacered Urea (Meth)Acrylates | METTL14, METTL3, FUS | EPHX1 3389/4885KDM4E 821/4885HTT 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.