Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.78 |
| ▸ | SQLE | Q14534 | 1/20 | 0.78 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3256599 | 1.00 | CYP2D6 (0.78) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| SCHEMBL5087616 | 0.89 | CYP2D6 (0.80) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| SCHEMBL5087608 | 0.89 | CYP2D6 (0.80) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| SCHEMBL9633991 | 0.88 | CYP2D6 (0.82) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| SCHEMBL9633984 | 0.88 | CYP2D6 (0.82) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| Terbinafine SCHEMBL37843 | 0.88 | CYP2D6 (1.00) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| Terbinafine SCHEMBL2028187 | 0.88 | CYP2D6 (1.00) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| Terbinafine SCHEMBL2042785 | 0.88 | CYP2D6 (1.00) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| Terbinafine SCHEMBL5279646 | 0.88 | CYP2D6 (1.00) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A | |
| Terbinafine SCHEMBL36794 | 0.88 | CYP2D6 (1.00) | CYP2D6LMNASLC6A2SIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261874-B1 | SPECIFIC MONOCLONAL ANTIBODY AGAINST TERBINAFINE | NOVARTIS AG (CH) | 2010-05-26 | — | — | EP | disclosed |
| US-7122184-B2 | Specific monoclonal antibody against terbinafine | NOVARTIS AG (CH) | 2006-10-17 | — | — | US | disclosed |
| US-20030087323-A1 | Specific monoclonal antibody against terbinafine | NOVARTIS AG (CH) | 2003-05-08 | — | — | US | disclosed |
| EP-1261874-A1 | SPECIFIC MONOCLONAL ANTIBODY AGAINST TERBINAFINE | Novartis AG (CH) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001059458-A1 | SPECIFIC MONOCLONAL ANTIBODY AGAINST TERBINAFINE | NOVARTIS AG (CH) | 2001-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087323-A1 | Specific monoclonal antibody against terbinafine | NEFM, CD69, PBK | CYP2D6 618/4885LMNA 3411/4885SLC6A2 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.