Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264614 | 0.87 | HTR6 (0.54) | HTR6CYP19A1TAAR1HDAC1HDAC10 | |
| SCHEMBL3252401 | 0.82 | HTR6 (0.44) | HTR6CYP19A1TAAR1FNTAFNTB | |
| SCHEMBL3250179 | 0.77 | HTR6 (0.58) | HTR6CYP19A1TAAR1HDAC1HDAC10 | |
| SCHEMBL3257361 | 0.76 | HTR6 (0.65) | HTR6HTR2AHDAC1HDAC8HDAC6 | |
| SCHEMBL3251339 | 0.76 | HTR6 (0.52) | HTR6CYP19A1TAAR1HDAC1HDAC10 | |
| SCHEMBL3257594 | 0.76 | HTR6 (0.60) | HTR6TAAR1HDAC1HDAC10HDAC8 | |
| SCHEMBL4431649 | 0.76 | HTR6 (0.52) | HTR6CYP19A1 | |
| SCHEMBL3248439 | 0.75 | HTR6 (0.51) | HTR6CYP19A1 | |
| SCHEMBL3253620 | 0.74 | HTR6 (0.69) | HTR6CYP19A1TAAR1HDAC1HDAC10 | |
| SCHEMBL3256595 | 0.74 | HTR6 (0.74) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537113-B9 | ARYLALKYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2010-05-26 | — | — | EP | disclosed |
| EP-1537113-B1 | ARYLALKYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LTD (IN) | 2009-10-07 | — | — | EP | disclosed |