⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14941726 | 0.74 | — | — | |
| SCHEMBL22792577 | 0.72 | — | — | |
| SCHEMBL18018476 | 0.67 | GPR84 (0.50) | — | |
| SCHEMBL14941725 | 0.67 | CA1 (0.44) | — | |
| SCHEMBL189997 | 0.67 | — | — | |
| SCHEMBL3362001 | 0.67 | — | — | |
| SCHEMBL1774205 | 0.67 | — | — | |
| SCHEMBL60308 | 0.67 | — | — | |
| SCHEMBL13918178 | 0.67 | — | — | |
| SCHEMBL1896344 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400497-A1 | 3CLPRO PROTEASE INHIBITOR | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. (CN) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023036140-A1 | 3CLPRO PROTEASE INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2023-03-16 | — | — | WO | disclosed |
| US-20170327471-A1 | Aryl sulphide and aryl sulphoxide derivatives having C-C-attached uracils as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-16 | — | — | US | disclosed |
| CN-107001288-A | Aryl thioether and aryl sulfoxide derivatives with C-C-linked uracils as pest control agents | 拜耳作物科学股份公司 | 2017-08-01 | — | — | CN | disclosed |
| US-20170204073-A1 | COMPOUNDS FOR NONSENSE SUPPRESSION, AND METHODS FOR THEIR USE | PTC THERAPEUTICS, INC. (US) | 2017-07-20 | — | — | US | disclosed |
| US-9611230-B2 | 1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS, INC. (US) | 2017-04-04 | — | — | US | disclosed |
| EP-2385042-B1 | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2015-11-25 | — | — | EP | disclosed |
| EP-2585068-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN | Janssen Pharmaceutica, N.V. (BE) | 2013-05-01 | — | — | EP | disclosed |
| EP-1866290-B1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2013-05-01 | — | — | EP | disclosed |
| EP-1866290-B1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2013-05-01 | — | — | EP | disclosed |
| US-20060235018-A1 | Prokineticin 1 receptor antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-19 | — | — | US | disclosed |
| WO-2006104715-A1 | PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006104713-A1 | PYRIMIDINDIONE DERIVATIVES AS PROKINETICIN 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| US-6017923-A | Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents | HOECHST MARION ROUSSEL, INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0705264-B1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMA INC (US) | 1999-04-07 | — | — | EP | disclosed |
| CN-1204648-A | Carbo-acyclic nucleoside derivatives as antiviral and antineoplastic agents | MERRELL PHARMA INC (US) | 1999-01-13 | — | — | CN | disclosed |
| CN-1040759-C | Carbo-acyclic nucleoside derivatives as antiviral and antitumor agents | MERRELL DOW PHARMA (US) | 1998-11-18 | — | — | CN | disclosed |
| CN-1125947-A | Carbo-acyclic nucleoside derivatives as antiviral and antitumor agents | MERRELL DOW PHARMA (US) | 1996-07-03 | — | — | CN | disclosed |
| EP-0705264-A1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000515-A1 | CARBO-ACYCLIC NUCLEOSIDE DERIVATIVES AS ANTIVIRAL AND ANTINEOPLASTIC AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |