⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726927 | 0.67 | CA1 (0.44) | — | |
| SCHEMBL1673294 | 0.67 | — | — | |
| SCHEMBL325682 | 0.67 | — | — | |
| SCHEMBL317622 | 0.67 | — | — | |
| SCHEMBL13918178 | 0.67 | — | — | |
| SCHEMBL8188652 | 0.67 | — | — | |
| SCHEMBL1896344 | 0.67 | — | — | |
| SCHEMBL1774205 | 0.67 | — | — | |
| SCHEMBL60308 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL30618396 | 0.65 | CA1 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177521-A1 | PROCESS FOR THE PREPARATION OF DEGARELIX | Fresenius Kabi Ipsum S.R.L. (IT) | 2022-06-09 | — | — | US | claimed |
| EP-3935072-A1 | PROCESS FOR THE PREPARATION OF DEGARELIX | Fresenius Kabi iPSUM S.r.l. (IT) | 2022-01-12 | — | — | EP | claimed |
| US-6359061-B1 | COMBINATORIAL LIBRARIES ARE USEFUL FOR SCREENING IN BIOLOGCAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | claimed |
| US-6316623-B1 | USEFUL FOR SCREENING IN BIOLOGICAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | claimed |
| US-5395838-A | Aromatic aminomethyl substitutes compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | claimed |
| EP-0373891-B1 | Anti-tumour agents | ICI PLC (GB) | 1994-11-02 | — | — | EP | claimed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| US-4386073-A | ANTIDOTES TO EFFECTS OF CERTAIN DRUGS | PATENTBUREAU DANUBIA (HU) | 1983-05-31 | — | — | US | claimed |
| US-3944550-A | Vitamin E orotate and a method of producing the same | KANEBO LTD. (JA) | 1976-03-16 | — | — | US | claimed |
| CN-116327957-A | Combination of agonist anti-PD-1 antibodies with GnRH agonists or GnRH antagonists for the treatment of cancer | 德彪药业国际股份公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-111727060-B | Agonist anti-PD-1 antibodies in combination with GnRH agonists or GnRH antagonists for the treatment of cancer | 德彪药业国际股份公司 | 2023-04-11 | — | — | CN | disclosed |
| US-20220177521-A1 | PROCESS FOR THE PREPARATION OF DEGARELIX | Fresenius Kabi Ipsum S.R.L. (IT) | 2022-06-09 | — | — | US | disclosed |
| EP-3935072-A1 | PROCESS FOR THE PREPARATION OF DEGARELIX | Fresenius Kabi iPSUM S.r.l. (IT) | 2022-01-12 | — | — | EP | disclosed |
| CN-111727060-A | Agonist anti-PD-1 antibodies in combination with GnRH agonists or GnRH antagonists for the treatment of cancer | 德彪药业国际股份公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-0373891-A2 | Anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |
| US-4725581-A | NERVOUS SYSTEM DISORDERS, COGNITION ACTIVATORS | ADIR ET COMPAGNIE (FR) | 1988-02-16 | — | — | US | disclosed |
| EP-0217688-A1 | Peptide derivatives with a lactonic or cycloamidic structure, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1987-04-08 | — | — | EP | disclosed |
| US-4386073-A | ANTIDOTES TO EFFECTS OF CERTAIN DRUGS | PATENTBUREAU DANUBIA (HU) | 1983-05-31 | — | — | US | disclosed |
| US-4386073-A | ANTIDOTES TO EFFECTS OF CERTAIN DRUGS | PATENTBUREAU DANUBIA (HU) | 1983-05-31 | — | — | US | disclosed |
| US-3944550-A | Vitamin E orotate and a method of producing the same | KANEBO LTD. (JA) | 1976-03-16 | — | — | US | disclosed |