SCHEMBL3257204

SCHEMBL3257204

NC1=NC(=O)c2nc(-c3ccccc3)c(-c3ccccc3)nc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 6/20 0.46
ADORA1 P30542 5/20 0.46
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
GLA P06280 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
XDH P47989 6/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
TLR9 Q9NR96 1/20 0.42
CSNK1A1 P48729 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DHFR P00374 1/20 0.40
PIK3CG P48736 1/20 0.40
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65673 0.73 KMT2A (0.59) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL14067780 0.72 TDP1 (0.48) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL14380289 0.71 KMT2A (0.56) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL23173620 0.70 CSNK1A1 (0.59) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL14733300 0.69 ADORA2A (0.60) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL31599316 0.69 ALDH1A1 (0.56) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL30395001 0.69 ALDH1A1 (0.56) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL10373895 0.69 MEN1 (0.50) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL5239315 0.67 ADK (0.61) ADORA2AADORA1ALDH1A1KDM4ELMNA
SCHEMBL12767600 0.67 NPC1 (0.57) ADORA2AADORA1ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134189-A Isocyanate, Imino Compound, Polymeric Binder MITSUBISHI PAPER MILLS LIMITED (JP) 1992-07-28 US claimed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
US-8980790-B2 Thermosensitive multiple recording sheet and method for producing the same OJI PAPER CO., LTD. (JP) 2015-03-17 US disclosed
US-20120274059-A1 THERMOSENSITIVE MULTIPLE RECORDING SHEET AND METHOD FOR PRODUCING THE SAME OJI PAPER CO., LTD. (JP) 2012-11-01 US disclosed
US-8252138-B2 Thermosensitive multiple recording sheet and method for producing the same OJI PAPER CO., LTD. (JP) 2012-08-28 US disclosed
US-20100003467-A1 THERMOSENSITIVE MULTIPLE RECORDING SHEET AND METHOD FOR PRODUCING THE SAME OJI PAPER CO., LTD. (JP) 2010-01-07 US disclosed
US-20070104081-A1 Recording sheet OJI PAPER CO., LTD. (JP) 2007-05-10 US disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
EP-0427929-B1 Heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1995-11-02 EP disclosed
US-5098738-A Coating a suspension of an isocyanate and an imino compound for color development and adjustment of pH with acid or base ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-03-24 US disclosed
US-5079211-A Reduced fogging, image storage stability, thermal printing MITSUBISHI PAPER MILLS LIMITED (JP) 1992-01-07 US disclosed
US-5043315-A Aromatic or heterocyclic isocyanate and imino compound MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
US-5043312-A Mixture of imino and isocyanate compounds, biphenyl alcohol in binder on support; image preservation, heat responsiveness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-08-27 US disclosed
EP-0439638-A1 Heat sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-08-07 EP disclosed
US-5036039-A Aromatic isocyanate and imine MITSUBISHI PAPER MILLS LIMITED (JP) 1991-07-30 US disclosed
EP-0427929-A2 Heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1991-05-22 EP disclosed
US-4965237-A AROMATICITY-POSESSING ISOCYANATE COMPOUND, IMINO COMPOUND, AND ANILINE DERIVATIVE MITSUBISHI PAPER MILLS, LTD. (JP) 1990-10-23 US disclosed
EP-0101741-B1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-05-20 EP disclosed
US-4521793-A Coloring method and color-forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-06-04 US disclosed