Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257467 | 1.00 | PTPN11 (0.47) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL3065774 | 0.82 | PTGDR2 (0.56) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL3257465 | 0.78 | PTPN11 (0.44) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL4905523 | 0.77 | MAPT (0.56) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL4462240 | 0.72 | KDM4E (0.57) | MAPTTRPM8RAB9AMEN1KMT2A | |
| SCHEMBL13761092 | 0.71 | PTPN11 (0.47) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL13761085 | 0.71 | SHMT1 (0.49) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 | |
| SCHEMBL3537226 | 0.70 | PTGDR2 (0.56) | SMN1; SMN2PTGDR2KDM4EPOLBALDH1A1 | |
| SCHEMBL9555373 | 0.69 | PTGDR2 (0.58) | MAPTRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL5937272 | 0.69 | PTPN11 (0.72) | PTPN11MAPTTRPM8RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225211-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | DU PONT (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| EP-2225211-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009086041-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | CYP1A1, CYP1B1, CBR3 | PTPN11 520/4885MAPT 4370/4885TRPM8 4005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.